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Modeling of glycerol production by fermentation in different reactor states
Alternative TitleProcess Biochem.
Xie, DM; Liu, DH; Liu, TZ
2001-06-01
Source PublicationPROCESS BIOCHEMISTRY
ISSN1359-5113
Volume36Issue:12Pages:1225-1232
AbstractA kinetic model of glycerol production by fermentation with the osmophilic yeast Candida krusei was studied firstly by analogies to published works. Considering that the glycerol produced competes with glucose, as a second carbon source for energy maintenance, mathematical models of glucose utilization and glycerol accumulation were modified further. By adjusting only two variable macrokinetic parameters, K-S and beta, the model simulations could fit experimental data well when the reactor was changed from Airlift Loop Reactor in different scale or airlift mode to Stirred Vessel. To avoid a significant reduction in glycerol production in the latter fermentation stage, the final condition of the fermentation, determined by the concentration ratio of glycerol to glucose, was also investigated in four different Reactor States. The kinetic models and simulation results can provide certain reference for scale up of glycerol production by fermentation. (C) 2001 Elsevier Science Ltd. All rights reserved.; A kinetic model of glycerol production by fermentation with the osmophilic yeast Candida krusei was studied firstly by analogies to published works. Considering that the glycerol produced competes with glucose, as a second carbon source for energy maintenance, mathematical models of glucose utilization and glycerol accumulation were modified further. By adjusting only two variable macrokinetic parameters, K-S and beta, the model simulations could fit experimental data well when the reactor was changed from Airlift Loop Reactor in different scale or airlift mode to Stirred Vessel. To avoid a significant reduction in glycerol production in the latter fermentation stage, the final condition of the fermentation, determined by the concentration ratio of glycerol to glucose, was also investigated in four different Reactor States. The kinetic models and simulation results can provide certain reference for scale up of glycerol production by fermentation. (C) 2001 Elsevier Science Ltd. All rights reserved.
KeywordKinetic Model Glycerol Fermentation Variable Parameters Reactor State Candida Krusei
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Technology
URL查看原文
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Engineering
WOS SubjectBiochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Engineering, Chemical
WOS IDWOS:000169948800010
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/5765
Collection研究所(批量导入)
Affiliation1.Tsing Hua Univ, Dept Chem Engn, Inst Appl Chem, Beijing 100084, Peoples R China
2.Chinese Acad Sci, Inst Chem Met, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Xie, DM,Liu, DH,Liu, TZ. Modeling of glycerol production by fermentation in different reactor states[J]. PROCESS BIOCHEMISTRY,2001,36(12):1225-1232.
APA Xie, DM,Liu, DH,&Liu, TZ.(2001).Modeling of glycerol production by fermentation in different reactor states.PROCESS BIOCHEMISTRY,36(12),1225-1232.
MLA Xie, DM,et al."Modeling of glycerol production by fermentation in different reactor states".PROCESS BIOCHEMISTRY 36.12(2001):1225-1232.
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