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Thesis Advisor李佐虎
Degree Grantor中国科学院研究生院
Other AbstractThe processes of fed-batch fermentation producing glutamic acid by the culture of Corynebacterium glutamicum T_(6-13) were studied. With the tests of environmental parameters the suitable time course and feed rate of the fed-batch culture were determined. The results are very good, the final average glutamic acid concentration 88.0g/l, maximum 91.2g/l, the average conversion of glucose to glutamic acid 62.3%, maximum 65.6%, the average fermentation time 30hr, minimum 28hr; During the fed-batch fermentation a linear relationship exists between the consumption of glucose and the amount of NH_3·H_2O added, the linear relative coefficient is above 0.996, based on which a control strategy for glucose feeding can be composed; To predict numerically the time course of the fed-batch culture, a simulating algorithm involving multiple linear regression analysis was used, which fit the experimental data essentially.
Document Type学位论文
Recommended Citation
GB/T 7714
陈建新. 谷氨酸发酵流加工艺及过程模拟与控制[D]. 中国科学院研究生院,1991.
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谷氨酸发酵流加工艺及过程模拟与控制.pd(2435KB) 限制开放CC BY-NC-SAApplication Full Text
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