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Effect of air flow rate on scleroglucan synthesis by Sclerotium glucanicum in an airlift bioreactor with an internal loop
Alternative TitleBioprocess Eng.
Kang, X; Wang, Y; Harvey, LM; McNeil, B
2000-07-01
Source PublicationBIOPROCESS ENGINEERING
ISSN0178-515X
Volume23Issue:1Pages:69-74
AbstractThe effect of air flow rate upon scleroglucan production in batch cultures of S. glucanicum NRRL 3006 cultivated in airlift reactor with internal loop was studied using air flow rates from 0.25 m(3)/h to 1.00 m(3)/h. Biomass formation was favoured at high air flow rates (with maximum biomass at 0.75 m(3)/h), whilst scleroglucan synthesis was highest at relatively low air flow rates (maximal at 0.40 m(3)/h). S. glucanicurn had a maximum specific growth rate of 0.018 h(-1) at 0.75 m(3)/h. The values of the key process optimisation parameters (scleroglucan yield, productivity and specific productivity) were all maximal at 0.4 m(3)/h. Since achievement of an adequate cell mass is essential for subsequent biopolymer synthesis, a bi-staged process was developed. In the first phase biomass formation was maximised by a high air flow rate of 0.75 m(3)/h, while in the second phase a lower air flow rate of 0.40 m(3)/h was used to stimulate biopolymer synthesis and minimise operational costs.; The effect of air flow rate upon scleroglucan production in batch cultures of S. glucanicum NRRL 3006 cultivated in airlift reactor with internal loop was studied using air flow rates from 0.25 m(3)/h to 1.00 m(3)/h. Biomass formation was favoured at high air flow rates (with maximum biomass at 0.75 m(3)/h), whilst scleroglucan synthesis was highest at relatively low air flow rates (maximal at 0.40 m(3)/h). S. glucanicurn had a maximum specific growth rate of 0.018 h(-1) at 0.75 m(3)/h.
KeywordAcid Production Exopolysaccharide Cultures Batch
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Technology
URL查看原文
Indexed BySCI
Language英语
WOS KeywordACID PRODUCTION ; EXOPOLYSACCHARIDE ; CULTURES ; BATCH
WOS Research AreaBiotechnology & Applied Microbiology ; Engineering
WOS SubjectBiotechnology & Applied Microbiology ; Engineering, Chemical
WOS IDWOS:000088592600012
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Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/5892
Collection研究所(批量导入)
Affiliation1.Univ Strathclyde, Dept Biosci & Biotechnol, Strathclyde Fermentat Ctr, Glasgow G1 1XW, Lanark, Scotland
2.Chinese Acad Sci, Inst Chem Met, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Kang, X,Wang, Y,Harvey, LM,et al. Effect of air flow rate on scleroglucan synthesis by Sclerotium glucanicum in an airlift bioreactor with an internal loop[J]. BIOPROCESS ENGINEERING,2000,23(1):69-74.
APA Kang, X,Wang, Y,Harvey, LM,&McNeil, B.(2000).Effect of air flow rate on scleroglucan synthesis by Sclerotium glucanicum in an airlift bioreactor with an internal loop.BIOPROCESS ENGINEERING,23(1),69-74.
MLA Kang, X,et al."Effect of air flow rate on scleroglucan synthesis by Sclerotium glucanicum in an airlift bioreactor with an internal loop".BIOPROCESS ENGINEERING 23.1(2000):69-74.
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