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Production of artemisinin by Artemisia annua hairy root culture in a internal loop airlift bioreactor
Alternative TitleActa Bot. Sin.
Liu, CZ; Wang, YC; Ouyang, F; Ye, HC; Li, GF
1999-02-01
Source PublicationACTA BOTANICA SINICA
ISSN0577-7496
Volume41Issue:2Pages:181-183
AbstractA self-made internal loop airlift bioreactor was used for production of artemisinin by Artemisia annua L. hairy root multi-plate culture. The hairy root cultures grew evenly either between the two meshes or attaching to the stainless steel meshes in the bioreactor. Under the optimal conditions of 12 h/d light cycle and 25 degrees C, the dry weight and artemisinin yield reached 22.57 g/L and 374.4 mg/L respectively after 20 days. Meantime, the kinetics of sugar, phosphate, nitrate and ammonium uptake during the course of culture were studied.; A self-made internal loop airlift bioreactor was used for production of artemisinin by Artemisia annua L. hairy root multi-plate culture. The hairy root cultures grew evenly either between the two meshes or attaching to the stainless steel meshes in the bioreactor. Under the optimal conditions of 12 h/d light cycle and 25 degrees C, the dry weight and artemisinin yield reached 22.57 g/L and 374.4 mg/L respectively after 20 days. Meantime, the kinetics of sugar, phosphate, nitrate and ammonium uptake during the course of culture were studied.
KeywordArtemisia Annua Internal Loop Airlift Bioreactor Hairy Root Artemisinin Kinetics
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
URL查看原文
Indexed BySCI
Language英语
WOS KeywordGROWTH
WOS Research AreaBiochemistry & Molecular Biology ; Plant Sciences
WOS SubjectBiochemistry & Molecular Biology ; Plant Sciences
WOS IDWOS:000079244300014
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/6033
Collection研究所(批量导入)
Affiliation1.Chinese Acad Sci, Inst Chem Met, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Inst Bot, Beijing 100093, Peoples R China
Recommended Citation
GB/T 7714
Liu, CZ,Wang, YC,Ouyang, F,et al. Production of artemisinin by Artemisia annua hairy root culture in a internal loop airlift bioreactor[J]. ACTA BOTANICA SINICA,1999,41(2):181-183.
APA Liu, CZ,Wang, YC,Ouyang, F,Ye, HC,&Li, GF.(1999).Production of artemisinin by Artemisia annua hairy root culture in a internal loop airlift bioreactor.ACTA BOTANICA SINICA,41(2),181-183.
MLA Liu, CZ,et al."Production of artemisinin by Artemisia annua hairy root culture in a internal loop airlift bioreactor".ACTA BOTANICA SINICA 41.2(1999):181-183.
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利用气升式内环流生物反应器培养青蒿毛状根(225KB) 限制开放CC BY-NC-SAApplication Full Text
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