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Production of artemisinin by shoot cultures of Artemisia annua L. in a modified inner-loop mist bioreactor
Alternative TitlePlant Sci.
Liu, CZ; Wang, YC; Guo, C; Ouyang, F; Ye, HC; Li, GF
1998-07-10
Source PublicationPLANT SCIENCE
ISSN0168-9452
Volume135Issue:2Pages:211-217
AbstractA modified inner-loop ultrasonic nutrient mist bioreactor with three stainless steel meshes was used to culture shoots of Artemisia annua L. for the production of artemisinin. The distribution of nutrient mist and the characteristics of shoot growth in the bioreactor were observed. Under the optimal misting cycle of 3/90 (3 min of misting ON, followed by 90 min of misting OFF), the dry weight of biomass and artemisinin production in the bioreactor reached 13.3 and 46.9 mg/l after 25 days. The growth and artemisinin accumulation in the mist bioreactor were higher than those in flasks. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.; A modified inner-loop ultrasonic nutrient mist bioreactor with three stainless steel meshes was used to culture shoots of Artemisia annua L. for the production of artemisinin. The distribution of nutrient mist and the characteristics of shoot growth in the bioreactor were observed. Under the optimal misting cycle of 3/90 (3 min of misting ON, followed by 90 min of misting OFF), the dry weight of biomass and artemisinin production in the bioreactor reached 13.3 and 46.9 mg/l after 25 days. The growth and artemisinin accumulation in the mist bioreactor were higher than those in flasks. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.
KeywordArtemisia Annua L. Artemisinin Misting Cycle Shoot Culture Modified Inner-loop Mist Bioreactor
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
URL查看原文
Indexed BySCI
Language英语
WOS KeywordQINGHAOSU ARTEMISININ ; ANTIMALARIAL DRUG ; TISSUE-CULTURES ; (+)-ARTEMISININ ; ROOTS
WOS Research AreaBiochemistry & Molecular Biology ; Plant Sciences
WOS SubjectBiochemistry & Molecular Biology ; Plant Sciences
WOS IDWOS:000075250700010
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/6036
Collection研究所(批量导入)
Affiliation1.Chinese Acad Sci, Inst Chem Met, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Inst Bot, Beijing 100093, Peoples R China
Recommended Citation
GB/T 7714
Liu, CZ,Wang, YC,Guo, C,et al. Production of artemisinin by shoot cultures of Artemisia annua L. in a modified inner-loop mist bioreactor[J]. PLANT SCIENCE,1998,135(2):211-217.
APA Liu, CZ,Wang, YC,Guo, C,Ouyang, F,Ye, HC,&Li, GF.(1998).Production of artemisinin by shoot cultures of Artemisia annua L. in a modified inner-loop mist bioreactor.PLANT SCIENCE,135(2),211-217.
MLA Liu, CZ,et al."Production of artemisinin by shoot cultures of Artemisia annua L. in a modified inner-loop mist bioreactor".PLANT SCIENCE 135.2(1998):211-217.
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