Analysis of Artemisinin in 1-Ethyl-3-Methylimidazolium Bromide-Water System by Reversed Phase High Performance Liquid Chromatography | |
Xia Yu-Jie1,2; Zeng Jian-Li1,2; Zhao Bing1; Wang Yu-Chuo1; Zhao, B | |
2009-04-01 | |
Source Publication | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
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ISSN | 0253-3820 |
Volume | 37Issue:4Pages:573-576 |
Abstract | A reversed phase high performance liquid chromatographic(RP-HPLC) method was developed for the quantitative analysis of artemisinin in a new ionic liquid system of 1-ethyl-3-methylimidazolium bromide-water. The determination was carried out on a C(18) column (250 mm x 4. 6 mm, 5 mu m) at room temperature (25 +/- 1) degrees C. Methanol-0.01 mol/l. HAc-NaAc (pH 5. 9) 60:40, V/V) was used as mobile phase at a flow rate of 0. 5 mL/min and detection wavelength was set at 260 nm. The calibration curve was a good linear relationship of artemisinin concentration in the range of 5 - 30 mg/L. The corresponding regression equation was y = 2. 20326 x 10(7)x - 30928. 7, r = 0. 9990. The recovery of artemisinin was 100. 2% and relative standard deviation was 0. 4%. |
Keyword | Artemisinin Ionic Liquid 1-ethyl-3-methylimidazolium Bromide Reversed Phase High Performance Liquid Chromatography |
Subtype | Article |
WOS Headings | Science & Technology ; Physical Sciences |
Indexed By | SCI |
Language | 英语 |
WOS Keyword | IONIC LIQUIDS ; ANTIMALARIAL-DRUG ; SEPARATION ; EXTRACTION |
WOS Research Area | Chemistry |
WOS Subject | Chemistry, Analytical |
WOS ID | WOS:000265617900019 |
Citation statistics | |
Document Type | 期刊论文 |
Version | 出版稿 |
Identifier | http://ir.ipe.ac.cn/handle/122111/6693 |
Collection | 生化工程国家重点实验室 |
Corresponding Author | Zhao, B |
Affiliation | 1.Chinese Acad Sci, Natl Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
Recommended Citation GB/T 7714 | Xia Yu-Jie,Zeng Jian-Li,Zhao Bing,et al. Analysis of Artemisinin in 1-Ethyl-3-Methylimidazolium Bromide-Water System by Reversed Phase High Performance Liquid Chromatography[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2009,37(4):573-576. |
APA | Xia Yu-Jie,Zeng Jian-Li,Zhao Bing,Wang Yu-Chuo,&Zhao, B.(2009).Analysis of Artemisinin in 1-Ethyl-3-Methylimidazolium Bromide-Water System by Reversed Phase High Performance Liquid Chromatography.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,37(4),573-576. |
MLA | Xia Yu-Jie,et al."Analysis of Artemisinin in 1-Ethyl-3-Methylimidazolium Bromide-Water System by Reversed Phase High Performance Liquid Chromatography".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 37.4(2009):573-576. |
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