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Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization
Alternative TitleAnal. Methods
Liu, Yuan2,3; Zhang, Guifeng2; Deng, Lihong1; Lei, Jiandu1; Wang, Lianyan2; He, Jing1
2014
Source PublicationANALYTICAL METHODS
ISSN1759-9660
Volume6Issue:3Pages:684-689
AbstractSynthesis of molecularly imprinted nanoparticles for tripterine with good selectivity and high adsorption capacity by precipitation polymerization is presented for the first time, in which tripterine, methacrylic acid and ethylene glycol dimethacrylate were used as a template molecule, functional monomer and cross-linker, respectively. The preparation conditions of molecularly imprinted nanoparticles were optimized, and the optimal molar ratio of template to functional monomer to cross-linker was 1 : 3 : 3. And non-imprinted polymers (NIPs) for control experiments were also prepared. The nanoparticles were characterized using a scanning electron microscope, laser particle size analyzer and BET, respectively. The results indicated that the imprinted nanoparticles were spherical in shape and the size was relatively uniform. Selectivity analysis suggested that the obtained imprinted nanoparticles could specifically recognize tripterine. In addition, adsorption kinetics and adsorption isotherm of the imprinted nanoparticles were utilized to study the binding characteristics of the imprinted nanoparticles. The results revealed that the imprinted nanoparticles had high adsorption capacity and the maximum adsorption capacity of tripterine on the imprinted particles was up to 145.97 mg g(-1). In potential application research, this adsorbent was satisfactorily employed as a solid-phase extraction sorbent to extract TTR in urine samples.; Synthesis of molecularly imprinted nanoparticles for tripterine with good selectivity and high adsorption capacity by precipitation polymerization is presented for the first time, in which tripterine, methacrylic acid and ethylene glycol dimethacrylate were used as a template molecule, functional monomer and cross-linker, respectively. The preparation conditions of molecularly imprinted nanoparticles were optimized, and the optimal molar ratio of template to functional monomer to cross-linker was 1 : 3 : 3. And non-imprinted polymers (NIPs) for control experiments were also prepared. The nanoparticles were characterized using a scanning electron microscope, laser particle size analyzer and BET, respectively. The results indicated that the imprinted nanoparticles were spherical in shape and the size was relatively uniform. Selectivity analysis suggested that the obtained imprinted nanoparticles could specifically recognize tripterine. In addition, adsorption kinetics and adsorption isotherm of the imprinted nanoparticles were utilized to study the binding characteristics of the imprinted nanoparticles. The results revealed that the imprinted nanoparticles had high adsorption capacity and the maximum adsorption capacity of tripterine on the imprinted particles was up to 145.97 mg g(-1). In potential application research, this adsorbent was satisfactorily employed as a solid-phase extraction sorbent to extract TTR in urine samples.
KeywordLiquid-chromatography Down-regulation Leukemia-cells Celastrol Apoptosis Separation Triterpene Inhibitor Arthritis Mice
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences ; Life Sciences & Biomedicine ; Technology
DOI10.1039/c3ay41772g
URL查看原文
Indexed BySCI
Language英语
WOS KeywordLIQUID-CHROMATOGRAPHY ; DOWN-REGULATION ; LEUKEMIA-CELLS ; CELASTROL ; APOPTOSIS ; SEPARATION ; TRITERPENE ; INHIBITOR ; ARTHRITIS ; MICE
WOS Research AreaChemistry ; Food Science & Technology ; Spectroscopy
WOS SubjectChemistry, Analytical ; Food Science & Technology ; Spectroscopy
WOS IDWOS:000330038500007
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Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/8226
Collection研究所(批量导入)
Affiliation1.Beijing Forestry Univ, Beijing Key Lab Lignocellulos Chem, Beijing 100083, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Liu, Yuan,Zhang, Guifeng,Deng, Lihong,et al. Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization[J]. ANALYTICAL METHODS,2014,6(3):684-689.
APA Liu, Yuan,Zhang, Guifeng,Deng, Lihong,Lei, Jiandu,Wang, Lianyan,&He, Jing.(2014).Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization.ANALYTICAL METHODS,6(3),684-689.
MLA Liu, Yuan,et al."Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization".ANALYTICAL METHODS 6.3(2014):684-689.
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