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Intravenous immunoglobulin improves glucose control and beta-cell function in human IAPP transgenic mice by attenuating islet inflammation and reducing IAPP oligomers 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 54, 页码: 145-152
Authors:  Zhang, Yue;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Shu-ying;  Liu, Xiang-meng;  Dong, Quan-xiu;  Chai, Jia-qian;  Liu, Rui-tian
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Type 2 Diabetes Mellitus  Intravenous Immunoglobulin  Islet Amyloid Polypeptide  Islet Inflammation  Toxic Oligomer  
Fruitless Wolfberry-Sprout Extract Rescued Cognitive Deficits and Attenuated Neuropathology in Alzheimer's Disease Transgenic Mice 期刊论文
CURRENT ALZHEIMER RESEARCH, 2018, 卷号: 15, 期号: 9, 页码: 856
Authors:  Liu, SY;  Lu, S;  Yu, XL;  Yang, SG;  Liu, W;  Liu, XM;  Wang, SW;  Zhu, J;  Ji, M;  Liu, DQ;  Zhang, ZP;  Liu, RT;  Liu, Shu-Ying;  Lu, Shuai;  Yu, Xiao-Lin;  Yang, Shi-Gao;  Liu, Wen;  Liu, Xiang-Meng;  Wang, Shao-Wei;  Zhu, Jie;  Ji, Mei;  Liu, Dong-Qun;  Zhang, Zi-Ping;  Liu, Rui-Tian
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Fruitless Wolfberry-sprout Extract  A-beta Oligomers  Alzheimer's Disease  Oxidative Stress  Amyloid-beta  Lycium-barbarum  Oligomers  Synaptic Plasticity  Neuroinflammation  Memory Deficits  Oxidative Stress  Spatial Memory  Neuroinflammation  Therapeutics  Mechanisms  Model  
A mimotope of A beta oligomers may also behave as a beta-sheet inhibitor 期刊论文
FEBS LETTERS, 2017, 卷号: 591, 期号: 21, 页码: 3615-3624
Authors:  Zhang, Yang-xin;  Wang, Shao-wei;  Lu, Shuai;  Zhang, Ling-xiao;  Liu, Dong-qun;  Ji, Mei;  Wang, Wei-yun;  Liu, Rui-tian
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Aggregation  Beta-amyloid Oligomer  Mimotope  Peptide  Vaccine  
Functional dipeptide derivatives: Molecular design, self-assembly and antitumor phototherapy 学位论文
, 北京: 中国科学院研究生院, 2017
Authors:  MANZAR ABBAS
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Self-assembly  Dipeptides  Porphyrin  Photothermal Therapy  Photodynamic Therapy  
A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer’s disease 期刊论文
Alzheimer's Research & Therapy, 2017, 卷号: 9, 期号: 1
Authors:  Wang,Shao-wei;  Liu,Dong-qun;  Zhang,Ling-xiao;  Ji,Mei;  Zhang,Yang-xin;  Dong,Quan-xiu;  Liu,Shu-ying;  Xie,Xi-xiu;  Liu,Rui-tian
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Alzheimer’s Disease  Β-amyloid Oligomer  Mimotope  Saccharomyces Cerevisiae  Vaccine  
A vaccine with A beta oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer's disease 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2017, 卷号: 9
Authors:  Wang, Shao-wei;  Liu, Dong-qun;  Zhang, Ling-xiao;  Ji, Mei;  Zhang, Yang-xin;  Dong, Quan-xiu;  Liu, Shu-ying;  Xie, Xi-xiu;  Liu, Rui-tian
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Alzheimer's Disease  Beta-amyloid Oligomer  Mimotope  Saccharomyces Cerevisiae  Vaccine  
A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: NOV, 页码: 36631
Authors:  Zha, Jun;  Liu, Xiang-meng;  Zhu, Jie;  Liu, Shu-ying;  Lu, Shuai;  Xu, Peng-xin;  Yu, Xiao-lin;  Liu, Rui-tian
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应用β-淀粉样蛋白寡聚体特异性表位疫苗及α-生育酚醌治疗阿尔茨海默病转基因小鼠的研究 学位论文
, 北京: 中国科学院研究生院, 2016
Authors:  王少伟
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Naturally occurring autoantibodies against A beta oligomers exhibited more beneficial effects in the treatment of mouse model of Alzheimer's disease than intravenous immunoglobulin 期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 105, 期号: JUNE, 页码: 561-576
Authors:  Wang, Teng;  Xie, Xi-xiu;  Ji, Mei;  Wang, Shao-wei;  Zha, Jun;  Zhou, Wei-wei;  Yu, Xiao-lin;  Wei, Chen;  Ma, Shan;  Xi, Zhi-ying;  Pang, Guang-li;  Liu, Rui-tian
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Alzheimer's Disease  Beta-amyloid  Intravenous Immunoglobulin  Oligomers  Antibody  
A Novel Multifunctional Compound Camellikaempferoside B Decreases A beta Production, Interferes with A beta Aggregation, and Prohibits A beta-Mediated Neurotoxicity and Neuroinflammation 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2016, 卷号: 7, 期号: 4, 页码: 505-518
Authors:  Yang, Shigao;  Liu, Wen;  Lu, Shuai;  Tian, Yong-zhen;  Wang, Wei-yun;  Ling, Tie-jun;  Liu, Rui-tian
Adobe PDF(2971Kb)  |  Favorite  |  View/Download:63/0  |  Submit date:2016/07/15
Amyloid-beta  Camellikaempferoside b  Beta-secretase  Aggregation  Neurotoxicity  Microglia