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Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2018, 卷号: 140, 页码: 157-167
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Ma, Xiaowei;  Hou, Baidong;  An, Wenqi;  Hua, Zhaolin;  Zhan, Jingjing;  Li, Yao;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
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Hbc-vlp  Hydrophobic Interaction Chromatography  Surface Hydrophobicity Properties  Rational Design  Vaccine Candidates  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
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Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
Authors:  Ji, M;  Xie, XX;  Liu, DQ;  Yu, XL;  Zhang, Y;  Zhang, LX;  Wang, SW;  Huang, YR;  Liu, RT;  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:32/0  |  Submit date:2018/12/29
Alzheimer's Disease  Virus-like Particles  Frontotemporal Dementia  In-vivo  Hepatitis b Core Protein  Neurofibrillary Degeneration  Truncated Tau  Corticobasal Degeneration  Neurofibrillary Tangles  Structural Determinants  Virus-like Particles (Vlps)  Truncated Tau  Vaccine  Immunotherapy  Protein  Pathology  Tauopathy  
新型Aβ42寡聚体模拟表位疫苗的制备 期刊论文
生物技术通报, 2017, 卷号: 33, 期号: 12, 页码: 87-92
Authors:  刘向蒙;  于雅东;  王少伟;  于晓琳;  王瑞明
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阿尔茨海默病  Aβ42寡聚体  模拟表位  疫苗  抗体  
应用β-淀粉样蛋白寡聚体特异性表位疫苗及α-生育酚醌治疗阿尔茨海默病转基因小鼠的研究 学位论文
, 北京: 中国科学院研究生院, 2016
Authors:  王少伟
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Immunogenicity and biodistribution of nanoparticles in vivo 期刊论文
EUROPEAN JOURNAL OF IMMUNOLOGY, 2016, 卷号: 46, 期号: AUG, 页码: 32-32
Authors:  Tsirikis, P.;  Wilson, K.;  Xiang, S.;  Wei, W.;  Ma, G.;  Selomulya, C.;  Plebanski, M.
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肠道病毒71型多表位融合抗原分离纯化及胞外自组装 学位论文
, 北京: 中国科学院研究生院, 2016
Authors:  薛玲
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肠道病毒71型  多表位融合抗原  手足口病疫苗  两步组合层析  复性及胞外自组装  
灭活病毒及病毒颗粒的结构表征和稳定性研究 学位论文
, 北京: 中国科学院研究生院, 2015
Authors:  杨延丽
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灭活病毒  病毒样颗粒  口蹄疫病毒  乙肝病毒表面抗原  稳定  
Size-exclusion HPLC provides a simple, rapid, and versatile alternative method for quality control of vaccines by characterizing the assembly of antigens 期刊论文
VACCINE, 2015, 卷号: 33, 期号: 9, 页码: 1143-1150
Authors:  Yang, Yanli;  Li, Hao;  Li, Zhengjun;  Zhang, Yan;  Zhang, Songping;  Chen, Yi;  Yu, Mengran;  Ma, Guanghui;  Su, Zhiguo
Adobe PDF(1723Kb)  |  Favorite  |  View/Download:101/0  |  Submit date:2015/05/12
Vaccine  Quality Control  Size-exclusion Hplc  Virus  Virus-like Particles