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A biomimetic VLP influenza vaccine with interior NP/exterior M2e antigens constructed through a temperature shift-based encapsulation strategy 期刊论文
VACCINE, 2020, 卷号: 38, 期号: 38, 页码: 5987-5996
Authors:  Wei, Jiangxue;  Li, Zhengjun;  Yang, Yanli;  Ma, Xiaowei;  An, Wenqi;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
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Influenza Vaccine  Virus Like-particles  Biomimetic  Nucleoprotein  M2e  
An Apoferritin-Hemagglutinin Conjugate Vaccine with Encapsulated Nucleoprotein Antigen Peptide from Influenza Virus Confers Enhanced Cross Protection 期刊论文
BIOCONJUGATE CHEMISTRY, 2020, 卷号: 31, 期号: 8, 页码: 1948-1959
Authors:  Wei, Jiangxue;  Li, Zhengjun;  Yang, Yanli;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
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A novel rapid modularized hepatitis B core virus-like particle-based platform for personalized cancer vaccine preparation via fixed-point coupling 期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 28, 页码: 13
Authors:  Ji, Mei;  Zhu, Jie;  Xie, Xi-xiu;  Liu, Dong-qun;  Wang, Bin;  Yu, Zhuo;  Liu, Rui-tian
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Hepatitis b Core Protein  Virus-like Particle (Vlp)  Personalized Cancer Vaccine  Spycatcher/spytag  t Cell Epitope  
乙肝核心病毒样颗粒稳定性的分子动力学模拟研究 学位论文
硕士: 中国科学院大学, 2020
Authors:  马艳艳
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Hbc-vlps,分子动力学模拟,介电常数,Mm-pbsa,结合自由能  
以病毒样颗粒为“底盘”的流感疫苗仿生合成 学位论文
博士: 中国科学院大学, 2020
Authors:  魏江雪
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流感疫苗,病毒样颗粒,仿生合成,疫苗合成学,加热装载  
基于聚乳酸微球佐剂的乙肝疫苗研究 学位论文
博士: 中国科学院大学, 2020
Authors:  卢婷
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聚乳酸微球,双十八烷基二甲基溴化铵,Sting刺激剂,慢性乙肝模型鼠,冻干  
HBc-based virus-like particle assembly from inclusion bodies using 2-methyl-2, 4-pentanediol 期刊论文
PROCESS BIOCHEMISTRY, 2020, 卷号: 89, 页码: 233-237
Authors:  Zhang, Yao;  Yin, Shuang;  Zhang, Bingyang;  Bi, Jingxiu;  Liu, Yongdong;  Su, Zhiguo
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Virus-like particle (VLP)  Hepatitis B virus core antigen (HBc)  Inclusion body  Assembly  Sodium dodecyl sulfate (SDS)  2-methyl-2, 4-pentanediol (MPD)  
Development of meningococcal polysaccharide conjugate vaccine that can elicit long-lasting and strong cellular immune response with hepatitis B core antigen virus-like particles as a novel carrier protein 期刊论文
VACCINE, 2019, 卷号: 37, 期号: 7, 页码: 956-964
Authors:  Xu, Lingling;  Li, Zhengjun;  Su, Zhiguo;  Yang, Yanli;  Ma, Guanghui;  Yu, Rong;  Zhang, Songping
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Neisseria meningitidis  Conjugate vaccine  Hepatitis B core antigen  Virus-like particles  
A two-step heat treatment of cell disruption supernatant enables efficient removal of host cell proteins before chromatographic purification of HBc particles 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1581, 页码: 71-79
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Liu, Lili;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
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Hepatitis b Core Protein  Thermal Stability  Particles  Purification  Host Cell Protein  Chromatography  
Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2018, 卷号: 140, 页码: 157-167
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Ma, Xiaowei;  Hou, Baidong;  An, Wenqi;  Hua, Zhaolin;  Zhan, Jingjing;  Li, Yao;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
Adobe PDF(2413Kb)  |  Favorite  |  View/Download:161/0  |  Submit date:2018/12/28
Hbc-vlp  Hydrophobic Interaction Chromatography  Surface Hydrophobicity Properties  Rational Design  Vaccine Candidates