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Conjugation of staphylokinase with the arabinogalactan-PEG conjugate: Study on the immunogenicity, in vitro bioactivity and pharmacokinetics 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 131, 页码: 896-904
Authors:  Qi, Fangbing;  Qi, Jinming;  Hu, Chunyang;  Shen, Lijuan;  Yu, Weili;  Hu, Tao
Favorite  |  View/Download:37/0  |  Submit date:2019/06/14
Staphylokinase  Arabinogalactan  Immunogenicity  Pharmacokinetic  PEG linker  in vitro activity  
Engineering Magnetosomes for Ferroptosis/Immunomodulation Synergism in Cancer 期刊论文
ACS NANO, 2019, 卷号: 13, 期号: 5, 页码: 5662-5673
Authors:  Zhang, Fan;  Li, Feng;  Lu, Gui-Hong;  Nie, Weidong;  Zhang, Lijun;  Lv, Yanlin;  Bao, Weier;  Gao, Xiaoyong;  Wei, Wei;  Pu, Kanyi;  Xie, Hai-Yan
Favorite  |  View/Download:1/0  |  Submit date:2019/09/03
biomimetic magnetosomes  PD-1 antibody  TGF-beta inhibitor  immunomodulation  ferroptosis  cancer therapy  
Development of meningococcal polysaccharide conjugate vaccine that can elicit long-lasting and strong cellular immune response with hepatitis B core antigen virus-like particles as a novel carrier protein 期刊论文
VACCINE, 2019, 卷号: 37, 期号: 7, 页码: 956-964
Authors:  Xu, Lingling;  Li, Zhengjun;  Su, Zhiguo;  Yang, Yanli;  Ma, Guanghui;  Yu, Rong;  Zhang, Songping
Favorite  |  View/Download:43/0  |  Submit date:2019/04/03
Neisseria meningitidis  Conjugate vaccine  Hepatitis B core antigen  Virus-like particles  
Unique stabilizing mechanism provided by biocompatible choline-based ionic liquids for inhibiting dissociation of inactivated foot-and-mouth disease virus particles 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 24, 页码: 13933-13939
Authors:  Lin, Xuan;  Yang, Yanli;  Li, Shuai;  Song, Yanmin;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
Favorite  |  View/Download:38/0  |  Submit date:2019/06/14
Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2018, 卷号: 140, 页码: 157-167
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Ma, Xiaowei;  Hou, Baidong;  An, Wenqi;  Hua, Zhaolin;  Zhan, Jingjing;  Li, Yao;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
Adobe PDF(2413Kb)  |  Favorite  |  View/Download:80/0  |  Submit date:2018/12/28
Hbc-vlp  Hydrophobic Interaction Chromatography  Surface Hydrophobicity Properties  Rational Design  Vaccine Candidates  
Conjugation of chitosan oligosaccharides enhances immune response to porcine circovirus vaccine by activating macrophages 期刊论文
IMMUNOBIOLOGY, 2018, 卷号: 223, 期号: 11, 页码: 663-670
Authors:  Zhang, Guiqiang;  Jia, Peiyuan;  Liu, Hongtao;  Hu, Tao;  Du, Yuguang
Adobe PDF(2482Kb)  |  Favorite  |  View/Download:48/0  |  Submit date:2018/12/04
Adjuvant  Chitosan Oligosaccharide  Conjugation  Porcine Circovirus Type 2 (Pcv2)  Macrophages  Toll-like Receptors  
Conjugation of chitosan oligosaccharides via a carrier protein markedly improves immunogenicity of porcine circovirus vaccine 期刊论文
GLYCOCONJUGATE JOURNAL, 2018, 卷号: 35, 期号: 5, 页码: 451-459
Authors:  Zhang, Guiqiang;  Jia, Peiyuan;  Liu, Hongtao;  Hu, Tao;  Du, Yuguang
Adobe PDF(1597Kb)  |  Favorite  |  View/Download:55/0  |  Submit date:2018/12/04
Porcine Circovirus Type 2 (Pcv2)  Chitosan Oligosaccharide  Conjugation  Adjuvant System  Carrier Protein  
以苯环为连接桥的肺炎多糖结合疫苗及其免疫学性质的研究 学位论文
硕士: 中国科学院研究生院, 2018
Authors:  卫东
Adobe PDF(1250Kb)  |  Favorite  |  View/Download:26/0  |  Submit date:2019/03/29
肺炎多糖结合疫苗,苯环,连接桥,免疫学性质  
壳寡糖修饰猪圆环病毒疫苗的免疫原性及作用机制研究 学位论文
博士: 中国科学院大学, 2018
Authors:  张贵强
Adobe PDF(7029Kb)  |  Favorite  |  View/Download:23/0  |  Submit date:2019/04/02
猪圆环病毒疫苗,壳寡糖,化学修饰,免疫应答,作用机制  
An indoleamine 2, 3-dioxygenase siRNA nanoparticle-coated and Trp2-displayed recombinant yeast vaccine inhibits melanoma tumor growth in mice 期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 273, 页码: 1-12
Authors:  Liu, Dong-qun;  Lu, Shuai;  Zhang, Ling-xiao;  Ji, Mei;  Liu, Shu-ying;  Wang, Shao-wei;  Liu, Rui-tian
Favorite  |  View/Download:59/0  |  Submit date:2018/06/11
Small Interfering Rna (siRna)  Indoleamine 2  Nanoparticle  3-dioxygenase (Ido)  Tyrosinase-related Protein 2 (Trp2)  Saccharomyces Cerevisiae  Melanoma Tumor