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Ellagic acid rescues motor and cognitive deficits in the R6/2 mouse model of Huntington's disease by lowering mutant huntingtin protein 期刊论文
FOOD & FUNCTION, 2020, 卷号: 11, 期号: 2, 页码: 1334-1348
Authors:  Sun, Xun;  Zhu, Jie;  Sun, Xiao-ying;  Ji, Mei;  Yu, Xiao-lin;  Liu, Rui-tian
Favorite  |  View/Download:8/0  |  Submit date:2020/05/06
An "Amyloid-beta Cleaner" for the Treatment of Alzheimer's Disease by Normalizing Microglial Dysfunction 期刊论文
ADVANCED SCIENCE, 2019, 页码: 12
Authors:  Liu, Ruiyuan;  Yang, Jun;  Liu, Linying;  Lu, Zhiguo;  Shi, Zhuyan;  Ji, Weihong;  Shen, Jie;  Zhang, Xin
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Alzheimer's Disease  a Beta  Microglia  Neuroinflammation  Phagocytosis  
Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease 期刊论文
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
Authors:  Huang, Ya-ru;  Xie, Xi-xiu;  Ji, Mei;  Yu, Xiao-lin;  Zhu, Jie;  Zhang, Ling-xiao;  Liu, Xiao-ge;  Wei, Chen;  Li, Gang;  Liu, Rui-tian
Favorite  |  View/Download:64/0  |  Submit date:2019/04/03
Parkinson's disease  alpha-Synuclein  Naturally occurring autoantibodies  A53T mice  WIG  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:87/0  |  Submit date:2018/07/17
Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
Positively Charged Polyprodrug Amphiphiles with Enhanced Drug Loading and Reactive Oxygen Species-Responsive Release Ability for Traceable Synergistic Therapy 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 期号: 11, 页码: 4164-4171
Authors:  Li, Yan;  Li, Yanhui;  Ji, Weihong;  Lu, Zhiguo;  Liu, Linying;  Shi, Yuanjie;  Ma, Guanghui;  Zhang, Xin
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Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
Authors:  Ji, M;  Xie, XX;  Liu, DQ;  Yu, XL;  Zhang, Y;  Zhang, LX;  Wang, SW;  Huang, YR;  Liu, RT;  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:50/0  |  Submit date:2018/12/29
Alzheimer's Disease  Virus-like Particles  Frontotemporal Dementia  In-vivo  Hepatitis b Core Protein  Neurofibrillary Degeneration  Truncated Tau  Corticobasal Degeneration  Neurofibrillary Tangles  Structural Determinants  Virus-like Particles (Vlps)  Truncated Tau  Vaccine  Immunotherapy  Protein  Pathology  Tauopathy  
Fruitless Wolfberry-Sprout Extract Rescued Cognitive Deficits and Attenuated Neuropathology in Alzheimer's Disease Transgenic Mice 期刊论文
CURRENT ALZHEIMER RESEARCH, 2018, 卷号: 15, 期号: 9, 页码: 856
Authors:  Liu, SY;  Lu, S;  Yu, XL;  Yang, SG;  Liu, W;  Liu, XM;  Wang, SW;  Zhu, J;  Ji, M;  Liu, DQ;  Zhang, ZP;  Liu, RT;  Liu, Shu-Ying;  Lu, Shuai;  Yu, Xiao-Lin;  Yang, Shi-Gao;  Liu, Wen;  Liu, Xiang-Meng;  Wang, Shao-Wei;  Zhu, Jie;  Ji, Mei;  Liu, Dong-Qun;  Zhang, Zi-Ping;  Liu, Rui-Tian
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Fruitless Wolfberry-sprout Extract  A-beta Oligomers  Alzheimer's Disease  Oxidative Stress  Amyloid-beta  Lycium-barbarum  Oligomers  Synaptic Plasticity  Neuroinflammation  Memory Deficits  Oxidative Stress  Spatial Memory  Neuroinflammation  Therapeutics  Mechanisms  Model  
A mimotope of A beta oligomers may also behave as a beta-sheet inhibitor 期刊论文
FEBS LETTERS, 2017, 卷号: 591, 期号: 21, 页码: 3615-3624
Authors:  Zhang, Yang-xin;  Wang, Shao-wei;  Lu, Shuai;  Zhang, Ling-xiao;  Liu, Dong-qun;  Ji, Mei;  Wang, Wei-yun;  Liu, Rui-tian
Adobe PDF(709Kb)  |  Favorite  |  View/Download:99/0  |  Submit date:2017/12/20
Aggregation  Beta-amyloid Oligomer  Mimotope  Peptide  Vaccine  
PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering A beta generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 46, 页码: 81001-81013
Authors:  Huang, Na;  Lu, Shuai;  Liu, Xiao-Ge;  Zhu, Jie;  Wang, Yu-Jiong;  Liu, Rui-Tian
Adobe PDF(2798Kb)  |  Favorite  |  View/Download:83/0  |  Submit date:2017/11/27
Alzheimer's Disease  Nanoparticles  Beta-amyloid  Curcumin  Peptide  
A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: NOV, 页码: 36631
Authors:  Zha, Jun;  Liu, Xiang-meng;  Zhu, Jie;  Liu, Shu-ying;  Lu, Shuai;  Xu, Peng-xin;  Yu, Xiao-lin;  Liu, Rui-tian
Adobe PDF(2382Kb)  |  Favorite  |  View/Download:132/0  |  Submit date:2016/12/26