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Traceable Nano-Biohybrid Complexes by One-Step Synthesis as CRISPR-Chem Vectors for Neurodegenerative Diseases Synergistic Treatment 期刊论文
ADVANCED MATERIALS, 2021, 页码: 10
Authors:  Shen, Jie;  Lu, Zhiguo;  Wang, Jianze;  Hao, Qiulian;  Ji, Weihong;  Wu, Yanyue;  Peng, Huan;  Zhao, Ruichen;  Yang, Jun;  Li, Yan;  Shi, Zhuyan;  Zhang, Xin
Favorite  |  View/Download:9/0  |  Submit date:2021/08/31
CRISPR  Cas9  CRISPR‐  chem vectors  neurodegenerative diseases synergistic treatment  one‐  step synthesis  traceable nano‐  biohybrid complexes  
Synaptic vesicle-inspired nanoparticles with spatiotemporally controlled release ability as a "nanoguard'' for synergistic treatment of synucleinopathies 期刊论文
MATERIALS HORIZONS, 2021, 卷号: 8, 期号: 4, 页码: 1199-1206
Authors:  Ji, Weihong;  Li, Yan;  Liu, Ruiyuan;  Lu, Zhiguo;  Liu, Linying;  Shi, Zhuyan;  Shen, Jie;  Zhang, Xin
Favorite  |  View/Download:7/0  |  Submit date:2021/08/31
Targeted exosome coating gene-chem nanocomplex as "nanoscavenger" for clearing alpha-synuclein and immune activation of Parkinson's disease 期刊论文
SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 50, 页码: 11
Authors:  Liu, Linying;  Li, Yan;  Peng, Huan;  Liu, Ruiyuan;  Ji, Weihong;  Shi, Zhuyan;  Shen, Jie;  Ma, Guanghui;  Zhang, Xin
Favorite  |  View/Download:14/0  |  Submit date:2021/03/29
Strategies and materials of SMARTnon-viral vectors: Overcoming the barriers for brain gene therapy 期刊论文
NANO TODAY, 2020, 卷号: 35, 页码: 22
Authors:  Li, Yan;  Liu, Linying;  Ji, Weihong;  Peng, Huang;  Zhao, Ruichen;  Zhang, Xin
Favorite  |  View/Download:14/0  |  Submit date:2021/03/29
Brain gene therapy  Non-viral vectors  Blood-brain barrier  Endosome trapping  Real-time non-invasive monitoring  
Advances of Nanoparticles for Leukemia Treatment 期刊论文
ACS BIOMATERIALS SCIENCE & ENGINEERING, 2020, 卷号: 6, 期号: 12, 页码: 6478-6489
Authors:  Shen, Jie;  Lu, Zhiguo;  Wang, Jianze;  Zhang, Tianlu;  Yang, Jun;  Li, Yan;  Liu, Guiying;  Zhang, Xin
Adobe PDF(7419Kb)  |  Favorite  |  View/Download:22/0  |  Submit date:2021/03/29
Leukemia  Nanoparticles  Delivery  Drugs  Microenvironment  
靶向纳米递送体系用于阿尔茨海默病治疗的研究 学位论文
博士: 中国科学院大学, 2020
Authors:  刘瑞瑗
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阿尔茨海默病,纳米颗粒,小胶质细胞,Β-淀粉样蛋白,Tau蛋白  
应用鞣花酸治疗亨廷顿舞蹈病转基因小鼠的研究 学位论文
硕士: 中国科学院大学, 2020
Authors:  孙勋
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亨廷顿舞蹈病,鞣花酸,神经炎症,寡聚体,自噬  
A novel thrombin inhibitory peptide discovered from leech using affinity chromatography combined with ultra-high performance liquid chromatography-high resolution mass spectroscopy 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1151, 页码: 8
Authors:  Huang, Qiuyang;  Gao, Qian;  Chai, Xiaoxin;  Ren, Wei;  Zhang, Guifeng;  Kong, Yingjun;  Zhang, Yan;  Gao, Jianping;  Lei, Xiongxin;  Ma, Li
Adobe PDF(2022Kb)  |  Favorite  |  View/Download:45/0  |  Submit date:2020/07/23
Thrombin  Bioactive Compound Screening  Affinity Chromatography  Uplc-hr-ms  Leech  Thrombin Inhibitory Activity  
A novel rapid modularized hepatitis B core virus-like particle-based platform for personalized cancer vaccine preparation via fixed-point coupling 期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 28, 页码: 13
Authors:  Ji, Mei;  Zhu, Jie;  Xie, Xi-xiu;  Liu, Dong-qun;  Wang, Bin;  Yu, Zhuo;  Liu, Rui-tian
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Hepatitis b Core Protein  Virus-like Particle (Vlp)  Personalized Cancer Vaccine  Spycatcher/spytag  t Cell Epitope  
帕金森病靶向输递体系用于基因-化药协同治疗的研究 学位论文
博士: 中国科学院大学, 2020
Authors:  刘霖颖
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帕金森病,Sirna,联合递送,仿生设计