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Conjugation of staphylokinase with the arabinogalactan-PEG conjugate: Study on the immunogenicity, in vitro bioactivity and pharmacokinetics 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 131, 页码: 896-904
Authors:  Qi, Fangbing;  Qi, Jinming;  Hu, Chunyang;  Shen, Lijuan;  Yu, Weili;  Hu, Tao
Favorite  |  View/Download:37/0  |  Submit date:2019/06/14
Staphylokinase  Arabinogalactan  Immunogenicity  Pharmacokinetic  PEG linker  in vitro activity  
以苯环为连接桥的肺炎多糖结合疫苗及其免疫学性质的研究 学位论文
硕士: 中国科学院研究生院, 2018
Authors:  卫东
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肺炎多糖结合疫苗,苯环,连接桥,免疫学性质  
Prompt and Robust Humoral Immunity Elicited by a Conjugated Chimeric Malaria Antigen with a Truncated Flagellin 期刊论文
BIOCONJUGATE CHEMISTRY, 2018, 卷号: 29, 期号: 3, 页码: 761-770
Authors:  Guo, Fangxia;  Liu, Yongdong;  Zhang, Chun;  Wang, Qi;  Wang, Lianyan;  Gao, Yuhui;  Bi, Jingxiu;  Wang, Heng;  Su, Zhiguo
Favorite  |  View/Download:64/0  |  Submit date:2018/06/11
Purification and characterization of a long-acting ciliary neurotrophic factor via genetically fused with an albumin-binding domain 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2017, 卷号: 139, 期号: NOV, 页码: 14-20
Authors:  Xu, Longfu;  Zhang, Chun;  Liu, Liping;  Zhang, Yao;  Wang, Qi;  Wang, Jian;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(1130Kb)  |  Favorite  |  View/Download:66/0  |  Submit date:2017/11/27
Ciliary Neurotrophic Factor  Albumin-binding Domain  Pegylation  Circulatory Half-life  Pharmacokinetic  
Development of long-acting ciliary neurotrophic factor by site-specific conjugation with different-sized polyethylene glycols and transferrin 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017, 卷号: 529, 期号: 1-2, 页码: 275-284
Authors:  Zhang, Chun;  Yu, Rong;  Li, Zenglan;  Feng, Cui;  Wang, Qi;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(2220Kb)  |  Favorite  |  View/Download:67/0  |  Submit date:2017/11/27
Pegylation  Transferrin Coupling  Long-acting  Ciliary Neurotrophic Factor  Anti-obese  
PEG定点修饰及白蛋白结合肽融合的长效策略 学位论文
, 北京: 中国科学院研究生院, 2017
Authors:  徐龙福
Adobe PDF(3856Kb)  |  Favorite  |  View/Download:92/0  |  Submit date:2018/06/13
药物半衰期  长效策略  聚乙二醇  巯基选择性修饰  白蛋白结合肽  
Functional dipeptide derivatives: Molecular design, self-assembly and antitumor phototherapy 学位论文
, 北京: 中国科学院研究生院, 2017
Authors:  MANZAR ABBAS
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Self-assembly  Dipeptides  Porphyrin  Photothermal Therapy  Photodynamic Therapy  
Self-Assembled Peptide- and Protein-Based Nanomaterials for Antitumor Photodynamic and Photothermal Therapy 期刊论文
ADVANCED MATERIALS, 2017, 卷号: 29, 期号: 12, 页码: 1605021
Authors:  Abbas, Manzar;  Zou, Qianli;  Li, Shukun;  Yan, Xuehai
Adobe PDF(5221Kb)  |  Favorite  |  View/Download:100/0  |  Submit date:2017/04/17
Effect of protein immunogenicity and PEG size and branching on the anti-PEG immune response to PEGylated proteins 期刊论文
PROCESS BIOCHEMISTRY, 2017, 卷号: 52, 页码: 183-191
Authors:  Wan, Xue;  Zhang, Juankun;  Yu, Weili;  Shen, Lijuan;  Ji, Shaoyang;  Hu, Tao
Adobe PDF(673Kb)  |  Favorite  |  View/Download:81/0  |  Submit date:2017/03/24
Immunogenicity  Pegylation  Anti-peg Antibody  Conjugation  
Ionic liquids and supercritical carbon dioxide: green and alternative reaction media for chemical processes 期刊论文
REVIEWS IN CHEMICAL ENGINEERING, 2016, 卷号: 32, 期号: 6, 页码: 587-609
Authors:  Liu, Ruixia;  Zhang, Peng;  Zhang, Suojiang;  Yan, Ting;  Xin, Jiayu;  Zhang, Xiangping
Adobe PDF(692Kb)  |  Favorite  |  View/Download:72/0  |  Submit date:2017/03/24
Chemical Process  Green Reaction Media  Ionic Liquids  Supercritical Co2