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Ellagic acid rescues motor and cognitive deficits in the R6/2 mouse model of Huntington's disease by lowering mutant huntingtin protein 期刊论文
FOOD & FUNCTION, 2020, 卷号: 11, 期号: 2, 页码: 1334-1348
Authors:  Sun, Xun;  Zhu, Jie;  Sun, Xiao-ying;  Ji, Mei;  Yu, Xiao-lin;  Liu, Rui-tian
Favorite  |  View/Download:3/0  |  Submit date:2020/05/06
Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease 期刊论文
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
Authors:  Huang, Ya-ru;  Xie, Xi-xiu;  Ji, Mei;  Yu, Xiao-lin;  Zhu, Jie;  Zhang, Ling-xiao;  Liu, Xiao-ge;  Wei, Chen;  Li, Gang;  Liu, Rui-tian
Favorite  |  View/Download:60/0  |  Submit date:2019/04/03
Parkinson's disease  alpha-Synuclein  Naturally occurring autoantibodies  A53T mice  WIG  
Resveratrol Rescues Tau-Induced Cognitive Deficits and Neuropathology in a Mouse Model of Tauopathy 期刊论文
CURRENT ALZHEIMER RESEARCH, 2019, 卷号: 16, 期号: 8, 页码: 710-722
Authors:  Sun, Xiao-Ying;  Dong, Quan-Xiu;  Zhu, Jie;  Sun, Xun;  Zhang, Li-Fan;  Qiu, Mandy;  Yu, Xiao-Lin;  Liu, Rui-Tian
Favorite  |  View/Download:11/0  |  Submit date:2019/12/02
Resveratrol  Alzheimer's disease  tau  oligomer  neuroinflammation  synapse loss  
Resveratrol alleviates motor and cognitive deficits and neuropathology in the A53T-synuclein mouse model of Parkinson's disease 期刊论文
FOOD & FUNCTION, 2018, 卷号: 9, 期号: 12, 页码: 6415-6427
Authors:  Zhang, Li-fan;  Yu, Xiao-lin;  Ji, Mei;  Liu, Shu-ying;  Wu, Xiao-ling;  Wang, Yu-jiong;  Liu, Rui-tian
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Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:82/0  |  Submit date:2018/07/17
Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
Authors:  Ji, M;  Xie, XX;  Liu, DQ;  Yu, XL;  Zhang, Y;  Zhang, LX;  Wang, SW;  Huang, YR;  Liu, RT;  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:45/0  |  Submit date:2018/12/29
Alzheimer's Disease  Virus-like Particles  Frontotemporal Dementia  In-vivo  Hepatitis b Core Protein  Neurofibrillary Degeneration  Truncated Tau  Corticobasal Degeneration  Neurofibrillary Tangles  Structural Determinants  Virus-like Particles (Vlps)  Truncated Tau  Vaccine  Immunotherapy  Protein  Pathology  Tauopathy  
A mimotope of A beta oligomers may also behave as a beta-sheet inhibitor 期刊论文
FEBS LETTERS, 2017, 卷号: 591, 期号: 21, 页码: 3615-3624
Authors:  Zhang, Yang-xin;  Wang, Shao-wei;  Lu, Shuai;  Zhang, Ling-xiao;  Liu, Dong-qun;  Ji, Mei;  Wang, Wei-yun;  Liu, Rui-tian
Adobe PDF(709Kb)  |  Favorite  |  View/Download:95/0  |  Submit date:2017/12/20
Aggregation  Beta-amyloid Oligomer  Mimotope  Peptide  Vaccine  
基于短肽配位自组装的纳米药物及其在肿瘤治疗中的应用 学位论文
, 北京: 中国科学院研究生院, 2017
Authors:  李永新
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短肽  Zn2++  配位自组装  纳米药物  肿瘤治疗  
Functional dipeptide derivatives: Molecular design, self-assembly and antitumor phototherapy 学位论文
, 北京: 中国科学院研究生院, 2017
Authors:  MANZAR ABBAS
Adobe PDF(5208Kb)  |  Favorite  |  View/Download:107/1  |  Submit date:2018/06/13
Self-assembly  Dipeptides  Porphyrin  Photothermal Therapy  Photodynamic Therapy  
A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: NOV, 页码: 36631
Authors:  Zha, Jun;  Liu, Xiang-meng;  Zhu, Jie;  Liu, Shu-ying;  Lu, Shuai;  Xu, Peng-xin;  Yu, Xiao-lin;  Liu, Rui-tian
Adobe PDF(2382Kb)  |  Favorite  |  View/Download:125/0  |  Submit date:2016/12/26