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In vitro preparation of uniform and nucleic acid free hepatitis B core particles through an optimized disassembly-purification-reassembly process 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 178, 页码: 7
Authors:  Zhang, Yao;  Liu, Yongdong;  Zhang, Bingyang;  Yin, Shuang;  Li, Xiunan;  Zhao, Dawei;  Wang, Weiying;  Bi, Jingxiu;  Su, Zhiguo
Favorite  |  View/Download:6/0  |  Submit date:2021/08/31
Hepatitis B core (HBc)  Uniform VLPs  Nucleic acid removal  Disassembly-purification-reassembly  
口蹄疫疫苗抗原的稳定策略及新佐剂的设计 学位论文
博士: 中国科学院大学, 2020
Authors:  林旋
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灭活口蹄疫病毒疫苗,稳定性,过渡金属离子,离子液体,乳液佐剂  
基于聚乳酸微球佐剂的乙肝疫苗研究 学位论文
博士: 中国科学院大学, 2020
Authors:  卢婷
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聚乳酸微球,双十八烷基二甲基溴化铵,Sting刺激剂,慢性乙肝模型鼠,冻干  
Engineered hepatitis B core virus-like particle carrier for precise and personalized Alzheimer's disease vaccine preparation via fixed-point coupling 期刊论文
APPLIED MATERIALS TODAY, 2020, 卷号: 19, 页码: 16
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Lu, Shuai;  Zhang, Ling-xiao;  Huang, Ya-ru;  Liu, Rui-tian
Favorite  |  View/Download:31/0  |  Submit date:2020/09/22
Alzheimer's disease  Virus-like particles (VLPs)  B cell epitope peptide  SpyCatcher/SpyTag  Th2-type immune response  
Biochemical engineering in China 期刊论文
REVIEWS IN CHEMICAL ENGINEERING, 2019, 卷号: 35, 期号: 8, 页码: 929-993
Authors:  Ding, Mingzhu;  Chen, Biqiang;  Ji, Xiaojun;  Zhou, Jingwen;  Wang, Huiyuan;  Tian, Xiwei;  Feng, Xudong;  Yue, Hua;  Zhou, Yongjin;  Wang, Hailong;  Wu, Jianping;  Yang, Pengpeng;  Jiang, Yu;  Mao, Xuming;  Xiao, Gang;  Zhong, Cheng;  Xiao, Wenhai;  Li, Bingzhi;  Qin, Lei;  Cheng, Jingsheng;  Yao, Mingdong;  Wang, Ying;  Liu, Hong;  Zhang, Lin;  Yu, Linling;  Chen, Tao;  Dong, Xiaoyan;  Jia, Xiaoqiang;  Zhang, Songping;  Liu, Yanfeng;  Chen, Yong;  Chen, Kequan;  Wu, Jinglan;  Zhu, Chenjie;  Zhuang, Wei;  Xu, Sheng;  Jiao, Pengfei;  Zhang, Lei;  Song, Hao;  Yang, Sheng;  Xiong, Yan;  Li, Yongquan;  Zhang, Youming;  Zhuang, Yingping;  Su, Haijia;  Fu, Weiping;  Huang, Yingming;  Li, Chun;  Zhao, Zongbao K.;  Sun, Yan;  Chen, Guo-Qiang;  Zhao, Xueming;  Huang, He;  Zheng, Yuguo;  Yang, Lirong;  Su, Zhiguo;  Ma, Guanghui;  Ying, Hanjie;  Chen, Jian;  Tan, Tianwei;  Yuan, Yingjin
Adobe PDF(10384Kb)  |  Favorite  |  View/Download:67/0  |  Submit date:2020/03/24
Biochemical Engineering  Food Chemical Engineering  Industrial Biotechnology  
A Novel Human Papillomavirus 16 L1 Pentamer-Loaded Hybrid Particles Vaccine System: Influence of Size on Immune Responses 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 42, 页码: 35745-35759
Authors:  Jia, Chengcheng;  Yang, Tingyuan;  Liu, Yongjiang;  Zhu, Ali;  Yin, Fei;  Wang, Yajun;  Xu, Lan;  Wang, Yan;  Yan, Mei;  Cai, Qingman;  Liang, Xiaoxu;  Ju, Ruijun;  Chen, Jianping;  Wang, Lianyan
Adobe PDF(6724Kb)  |  Favorite  |  View/Download:143/0  |  Submit date:2018/12/04
Human Papillomavirus  Pentamer  Particle  Size  Adjuvant  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
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Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
Authors:  Ji, M;  Xie, XX;  Liu, DQ;  Yu, XL;  Zhang, Y;  Zhang, LX;  Wang, SW;  Huang, YR;  Liu, RT;  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:86/0  |  Submit date:2018/12/29
Alzheimer's Disease  Virus-like Particles  Frontotemporal Dementia  In-vivo  Hepatitis b Core Protein  Neurofibrillary Degeneration  Truncated Tau  Corticobasal Degeneration  Neurofibrillary Tangles  Structural Determinants  Virus-like Particles (Vlps)  Truncated Tau  Vaccine  Immunotherapy  Protein  Pathology  Tauopathy  
High hydrostatic pressure encapsulation of doxorubicin in ferritin nanocages with enhanced efficiency 期刊论文
JOURNAL OF BIOTECHNOLOGY, 2017, 卷号: 254, 页码: 34-42
Authors:  Wang, Qi;  Zhang, Chun;  Liu, Liping;  Lia, Zenglan;  Guo, Fangxia;  Li, Xiunan;  Luo, Jian;  Zhao, Dawei;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(1237Kb)  |  Favorite  |  View/Download:163/0  |  Submit date:2017/09/06
High Hydrostatic Pressure  Anticancer Drug  Human Ferritin  Doxorubicin  Encapsulation  Nanoparticle  
基于碳酸钙微球的乙肝疫苗佐剂构建及免疫增强效果的研究 学位论文
, 北京: 中国科学院研究生院, 2017
Authors:  贾吉磊
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碳酸钙微球  颗粒型佐剂  表面电荷  粒径效应  Dc靶向