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Immunization with a fusion protein vaccine candidate generated from truncated peptides of human enterovirus 71 protects mice from lethal enterovirus 71 infections 期刊论文
Virology Journal, 2020, 卷号: 17, 期号: 1
Authors:  Liu,Jiangning;  Zhao,Binbin;  Xue,Ling;  Wu,Jing;  Xu,Yanfeng;  Liu,Yongdong;  Qin,Chuan
Favorite  |  View/Download:5/0  |  Submit date:2020/05/21
Human Enterovirus 71  Vaccine candidate  Fusion protein  Mouse model  Infection  
Mechanism of bio-macromolecule denaturation on solid-liquid surface of ion-exchange chromatographic media - A case study for inactivated foot-and-mouth disease virus 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1142, 页码: 10
Authors:  Yang, Yanli;  Song, Yanmin;  Lin, Xuan;  Li, Shuai;  Li, Zhengjun;  Zhao, Qizu;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
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Differential scanning calorimetry  Solid-liquid interface  Ion exchange chromatography  Foot-and-mouth disease virus  Dissociation  Stability  
HBc-based virus-like particle assembly from inclusion bodies using 2-methyl-2, 4-pentanediol 期刊论文
PROCESS BIOCHEMISTRY, 2020, 卷号: 89, 页码: 233-237
Authors:  Zhang, Yao;  Yin, Shuang;  Zhang, Bingyang;  Bi, Jingxiu;  Liu, Yongdong;  Su, Zhiguo
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Virus-like particle (VLP)  Hepatitis B virus core antigen (HBc)  Inclusion body  Assembly  Sodium dodecyl sulfate (SDS)  2-methyl-2, 4-pentanediol (MPD)  
Biochemical engineering in China 期刊论文
REVIEWS IN CHEMICAL ENGINEERING, 2019, 卷号: 35, 期号: 8, 页码: 929-993
Authors:  Ding, Mingzhu;  Chen, Biqiang;  Ji, Xiaojun;  Zhou, Jingwen;  Wang, Huiyuan;  Tian, Xiwei;  Feng, Xudong;  Yue, Hua;  Zhou, Yongjin;  Wang, Hailong;  Wu, Jianping;  Yang, Pengpeng;  Jiang, Yu;  Mao, Xuming;  Xiao, Gang;  Zhong, Cheng;  Xiao, Wenhai;  Li, Bingzhi;  Qin, Lei;  Cheng, Jingsheng;  Yao, Mingdong;  Wang, Ying;  Liu, Hong;  Zhang, Lin;  Yu, Linling;  Chen, Tao;  Dong, Xiaoyan;  Jia, Xiaoqiang;  Zhang, Songping;  Liu, Yanfeng;  Chen, Yong;  Chen, Kequan;  Wu, Jinglan;  Zhu, Chenjie;  Zhuang, Wei;  Xu, Sheng;  Jiao, Pengfei;  Zhang, Lei;  Song, Hao;  Yang, Sheng;  Xiong, Yan;  Li, Yongquan;  Zhang, Youming;  Zhuang, Yingping;  Su, Haijia;  Fu, Weiping;  Huang, Yingming;  Li, Chun;  Zhao, Zongbao K.;  Sun, Yan;  Chen, Guo-Qiang;  Zhao, Xueming;  Huang, He;  Zheng, Yuguo;  Yang, Lirong;  Su, Zhiguo;  Ma, Guanghui;  Ying, Hanjie;  Chen, Jian;  Tan, Tianwei;  Yuan, Yingjin
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Biochemical Engineering  Food Chemical Engineering  Industrial Biotechnology  
Development of meningococcal polysaccharide conjugate vaccine that can elicit long-lasting and strong cellular immune response with hepatitis B core antigen virus-like particles as a novel carrier protein 期刊论文
VACCINE, 2019, 卷号: 37, 期号: 7, 页码: 956-964
Authors:  Xu, Lingling;  Li, Zhengjun;  Su, Zhiguo;  Yang, Yanli;  Ma, Guanghui;  Yu, Rong;  Zhang, Songping
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Neisseria meningitidis  Conjugate vaccine  Hepatitis B core antigen  Virus-like particles  
Unique stabilizing mechanism provided by biocompatible choline-based ionic liquids for inhibiting dissociation of inactivated foot-and-mouth disease virus particles 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 24, 页码: 13933-13939
Authors:  Lin, Xuan;  Yang, Yanli;  Li, Shuai;  Song, Yanmin;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
Favorite  |  View/Download:56/0  |  Submit date:2019/06/14
Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2018, 卷号: 140, 页码: 157-167
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Ma, Xiaowei;  Hou, Baidong;  An, Wenqi;  Hua, Zhaolin;  Zhan, Jingjing;  Li, Yao;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
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Hbc-vlp  Hydrophobic Interaction Chromatography  Surface Hydrophobicity Properties  Rational Design  Vaccine Candidates  
Effect of Pore Structure on Protein Capacity in Macroporous Polymer Chromatographic Supports 期刊论文
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2018, 卷号: 39, 期号: 12, 页码: 2673-2678
Authors:  Li Heng;  Wang Shaoyun;  Fang Jiaxuan;  Zhao Lan;  Jin Haibo;  He Guangxiang;  Guo Xiaoyan;  Gu Qingyang;  Hao Siwen;  Re Ziya;  Zhi Weijie;  Yu Hongbin;  Zhang Rongyue
Adobe PDF(443Kb)  |  Favorite  |  View/Download:82/0  |  Submit date:2019/04/03
Macroporous Polymer Microsphere  Chromatographic Media  Protein Capactiy  High Through-put  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:87/0  |  Submit date:2018/07/17
Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
Preparation and Application of Porous Polymer Microspheres in Virus-Like Particles Purification 期刊论文
PROGRESS IN CHEMISTRY, 2018, 卷号: 30, 期号: 1, 页码: 5-13
Authors:  Na, Xiangming;  Zhou, Weiqing;  Li, Juan;  Su, Zhiguo;  Ma, Guanghui
Favorite  |  View/Download:110/0  |  Submit date:2018/06/11
Porous Microspheres  Gigaporous Microspheres  Virus-like Particles (Vlps)  Separation And Purification Of Biomacromolecules