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Development of meningococcal polysaccharide conjugate vaccine that can elicit long-lasting and strong cellular immune response with hepatitis B core antigen virus-like particles as a novel carrier protein 期刊论文
VACCINE, 2019, 卷号: 37, 期号: 7, 页码: 956-964
Authors:  Xu, Lingling;  Li, Zhengjun;  Su, Zhiguo;  Yang, Yanli;  Ma, Guanghui;  Yu, Rong;  Zhang, Songping
Favorite  |  View/Download:56/0  |  Submit date:2019/04/03
Neisseria meningitidis  Conjugate vaccine  Hepatitis B core antigen  Virus-like particles  
Unique stabilizing mechanism provided by biocompatible choline-based ionic liquids for inhibiting dissociation of inactivated foot-and-mouth disease virus particles 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 24, 页码: 13933-13939
Authors:  Lin, Xuan;  Yang, Yanli;  Li, Shuai;  Song, Yanmin;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
Favorite  |  View/Download:48/0  |  Submit date:2019/06/14
Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2018, 卷号: 140, 页码: 157-167
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Ma, Xiaowei;  Hou, Baidong;  An, Wenqi;  Hua, Zhaolin;  Zhan, Jingjing;  Li, Yao;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
Adobe PDF(2413Kb)  |  Favorite  |  View/Download:88/0  |  Submit date:2018/12/28
Hbc-vlp  Hydrophobic Interaction Chromatography  Surface Hydrophobicity Properties  Rational Design  Vaccine Candidates  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:75/0  |  Submit date:2018/07/17
Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
Preparation and Application of Porous Polymer Microspheres in Virus-Like Particles Purification 期刊论文
PROGRESS IN CHEMISTRY, 2018, 卷号: 30, 期号: 1, 页码: 5-13
Authors:  Na, Xiangming;  Zhou, Weiqing;  Li, Juan;  Su, Zhiguo;  Ma, Guanghui
Favorite  |  View/Download:97/0  |  Submit date:2018/06/11
Porous Microspheres  Gigaporous Microspheres  Virus-like Particles (Vlps)  Separation And Purification Of Biomacromolecules  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
Authors:  Ji, M;  Xie, XX;  Liu, DQ;  Yu, XL;  Zhang, Y;  Zhang, LX;  Wang, SW;  Huang, YR;  Liu, RT;  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:39/0  |  Submit date:2018/12/29
Alzheimer's Disease  Virus-like Particles  Frontotemporal Dementia  In-vivo  Hepatitis b Core Protein  Neurofibrillary Degeneration  Truncated Tau  Corticobasal Degeneration  Neurofibrillary Tangles  Structural Determinants  Virus-like Particles (Vlps)  Truncated Tau  Vaccine  Immunotherapy  Protein  Pathology  Tauopathy  
基于碳酸钙微球的乙肝疫苗佐剂构建及免疫增强效果的研究 学位论文
, 北京: 中国科学院研究生院, 2017
Authors:  贾吉磊
Adobe PDF(9401Kb)  |  Favorite  |  View/Download:156/2  |  Submit date:2018/06/13
碳酸钙微球  颗粒型佐剂  表面电荷  粒径效应  Dc靶向  
灭活口蹄疫病毒抗原的离子交换色谱纯化 学位论文
, 北京: 中国科学院研究生院, 2017
Authors:  梁山琴
Adobe PDF(3231Kb)  |  Favorite  |  View/Download:89/1  |  Submit date:2018/06/13
灭活口蹄疫病毒  离子交换色谱  差示扫描量热仪  稳定性  解聚  
Purification and assembling a fused capsid protein as an enterovirus 71 vaccine candidate from inclusion bodies to pentamer-based nanoparticles 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2017, 卷号: 117, 页码: 139-146
Authors:  Xue, Ling;  Liu, Jiangning;  Wang, Qi;  Zhang, Chun;  Xu, Longfu;  Luo, Jian;  Wang, Jian;  Qin, Chuan;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(1568Kb)  |  Favorite  |  View/Download:86/0  |  Submit date:2017/03/24
Enterovirus 71 (Ev71)  Virus-like Particles (Vlps)  Assembling  Fused Antigen  Inclusion Bodies  
壳聚糖季铵盐凝乳胶微球对O型口蹄疫VLPs免疫豚鼠的免疫增强作用 期刊论文
中国兽医科学, 2017, 卷号: 47, 期号: 10, 页码: 1240-1244
Authors:  朱向涛;  孙世琪;  吴颉;  郭慧琛;  马军武
Adobe PDF(1844Kb)  |  Favorite  |  View/Download:47/0  |  Submit date:2018/09/05
壳聚糖季铵盐凝乳胶微球  口蹄疫病毒  病毒样颗粒  佐剂