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Vaccines targeting the primary amino acid sequence and conformational epitope of amyloid-beta had distinct effects on neuropathology and cognitive deficits in EAE/AD mice 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 页码: 12
Authors:  Yu, Xiao-Lin;  Zhu, Jie;  Liu, Xiang-meng;  Xu, Peng-xin;  Zhang, Yue;  Liu, Rui-tian
Favorite  |  View/Download:8/0  |  Submit date:2020/05/21
An "Amyloid-beta Cleaner" for the Treatment of Alzheimer's Disease by Normalizing Microglial Dysfunction 期刊论文
ADVANCED SCIENCE, 2019, 页码: 12
Authors:  Liu, Ruiyuan;  Yang, Jun;  Liu, Linying;  Lu, Zhiguo;  Shi, Zhuyan;  Ji, Weihong;  Shen, Jie;  Zhang, Xin
Adobe PDF(2682Kb)  |  Favorite  |  View/Download:17/0  |  Submit date:2020/03/24
Alzheimer's Disease  a Beta  Microglia  Neuroinflammation  Phagocytosis  
Metal-Ion Modulated Structural Transformation of Amyloid-Like Dipeptide Supramolecular Self-Assembly 期刊论文
ACS NANO, 2019, 卷号: 13, 期号: 6, 页码: 7300-7309
Authors:  Ji, Wei;  Yuan, Chengqian;  Zilberzwige-Tal, Shai;  Xin, Ruirui;  Chakraborty, Priyadarshi;  Tao, Kai;  Gilead, Sharon;  Yan, Xuehai;  Gazit, Ehud
Favorite  |  View/Download:29/0  |  Submit date:2019/09/03
hydrogels  self-assembly  nanostructures  dipeptide  supramolecular chemistry  
Peptide-modulated self-assembly as a versatile strategy for tumor supramolecular nanotheranostics 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 11, 页码: 3249-3261
Authors:  Li, Shukun;  Zou, Qianli;  Xing, Ruirui;  Govindaraju, Thimmaiah;  Fakhrullin, Rawil;  Yan, Xuehai
Favorite  |  View/Download:70/0  |  Submit date:2019/06/14
peptides  self-assembly  intermolecular interactions  nanotheranostics  cancer  
Resveratrol Rescues Tau-Induced Cognitive Deficits and Neuropathology in a Mouse Model of Tauopathy 期刊论文
CURRENT ALZHEIMER RESEARCH, 2019, 卷号: 16, 期号: 8, 页码: 710-722
Authors:  Sun, Xiao-Ying;  Dong, Quan-Xiu;  Zhu, Jie;  Sun, Xun;  Zhang, Li-Fan;  Qiu, Mandy;  Yu, Xiao-Lin;  Liu, Rui-Tian
Favorite  |  View/Download:28/0  |  Submit date:2019/12/02
Resveratrol  Alzheimer's disease  tau  oligomer  neuroinflammation  synapse loss  
Delivery systems for theranostics in neurodegenerative diseases 期刊论文
NANO RESEARCH, 2018, 卷号: 11, 期号: 10, 页码: 5535-5555
Authors:  Li, Yan;  Liu, Ruiyuan;  Ji, Weihong;  Li, Yanhui;  Liu, Linying;  Zhang, Xin
Adobe PDF(2919Kb)  |  Favorite  |  View/Download:77/0  |  Submit date:2018/12/04
Neurodegenerative Diseases  Theranostics  Blood-brain Barrier  Delivery Systems  
Charge-Induced Secondary Structure Transformation of Amyloid-Derived Dipeptide Assemblies from beta-Sheet to alpha-Helix 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 6, 页码: 1537-1542
Authors:  Xing, Ruirui;  Yuan, Chengqian;  Li, Shukun;  Song, Jingwen;  Li, Junbai;  Yan, Xuehai
Adobe PDF(3733Kb)  |  Favorite  |  View/Download:100/0  |  Submit date:2018/06/11
Gels  Nanofibers  Peptides  Phase Transitions  Self-assembly  
Intravenous immunoglobulin improves glucose control and beta-cell function in human IAPP transgenic mice by attenuating islet inflammation and reducing IAPP oligomers 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 54, 页码: 145-152
Authors:  Zhang, Yue;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Shu-ying;  Liu, Xiang-meng;  Dong, Quan-xiu;  Chai, Jia-qian;  Liu, Rui-tian
Favorite  |  View/Download:66/0  |  Submit date:2018/06/11
Type 2 Diabetes Mellitus  Intravenous Immunoglobulin  Islet Amyloid Polypeptide  Islet Inflammation  Toxic Oligomer  
Fruitless Wolfberry-Sprout Extract Rescued Cognitive Deficits and Attenuated Neuropathology in Alzheimer's Disease Transgenic Mice 期刊论文
CURRENT ALZHEIMER RESEARCH, 2018, 卷号: 15, 期号: 9, 页码: 856
Authors:  Liu, SY;  Lu, S;  Yu, XL;  Yang, SG;  Liu, W;  Liu, XM;  Wang, SW;  Zhu, J;  Ji, M;  Liu, DQ;  Zhang, ZP;  Liu, RT;  Liu, Shu-Ying;  Lu, Shuai;  Yu, Xiao-Lin;  Yang, Shi-Gao;  Liu, Wen;  Liu, Xiang-Meng;  Wang, Shao-Wei;  Zhu, Jie;  Ji, Mei;  Liu, Dong-Qun;  Zhang, Zi-Ping;  Liu, Rui-Tian
Adobe PDF(2502Kb)  |  Favorite  |  View/Download:89/0  |  Submit date:2018/12/29
Fruitless Wolfberry-sprout Extract  A-beta Oligomers  Alzheimer's Disease  Oxidative Stress  Amyloid-beta  Lycium-barbarum  Oligomers  Synaptic Plasticity  Neuroinflammation  Memory Deficits  Oxidative Stress  Spatial Memory  Neuroinflammation  Therapeutics  Mechanisms  Model  
Trace Water as Prominent Factor to Induce Peptide Self-Assembly: Dynamic Evolution and Governing Interactions in Ionic Liquids 期刊论文
SMALL, 2017, 卷号: 13, 期号: 44, 页码: 1702175
Authors:  Wang, Juan;  Yuan, Chengqian;  Han, Yuchun;  Wang, Yilin;  Liu, Xiaomin;  Zhang, Suojiang;  Yan, Xuehai
Adobe PDF(3591Kb)  |  Favorite  |  View/Download:112/0  |  Submit date:2018/01/15
Dipeptide  Ionic Liquid  Kinetics And Thermodynamics  Self-assembly  Trace Water