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Development of purification process for dual-function recombinant human heavy-chain ferritin by the investigation of genetic modification impact on conformation 期刊论文
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 13
Authors:  Yin, Shuang;  Zhang, Bingyang;  Lin, Jianying;  Liu, Yongdong;  Su, Zhiguo;  Bi, Jingxiu
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ferritin E-helix turnover  ferritin genetic modification  human heavy-chain ferritin  protein characterization  protein purification  
Cost-effective purification process development for chimeric hepatitis B core (HBc) virus-like particles assisted by molecular dynamic simulation 期刊论文
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 15
Authors:  Zhang, Bingyang;  Yin, Shuang;  Wang, Yingli;  Su, Zhiguo;  Bi, Jingxiu
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hepatitis B core  molecular dynamic simulation  protein characterization  protein purification  virus‐  like particle  
Engineered Human Heavy-Chain Ferritin with Half-Life Extension and Tumor Targeting by PAS and RGDK Peptide Functionalization 期刊论文
PHARMACEUTICS, 2021, 卷号: 13, 期号: 4, 页码: 16
Authors:  Yin, Shuang;  Wang, Yan;  Zhang, Bingyang;  Qu, Yiran;  Liu, Yongdong;  Dai, Sheng;  Zhang, Yao;  Wang, Yingli;  Bi, Jingxiu
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ferritin  drug delivery  tumor targeting  half-life extension  
In vitro preparation of uniform and nucleic acid free hepatitis B core particles through an optimized disassembly-purification-reassembly process 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 178, 页码: 7
Authors:  Zhang, Yao;  Liu, Yongdong;  Zhang, Bingyang;  Yin, Shuang;  Li, Xiunan;  Zhao, Dawei;  Wang, Weiying;  Bi, Jingxiu;  Su, Zhiguo
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Hepatitis B core (HBc)  Uniform VLPs  Nucleic acid removal  Disassembly-purification-reassembly  
HBc-based virus-like particle assembly from inclusion bodies using 2-methyl-2, 4-pentanediol 期刊论文
PROCESS BIOCHEMISTRY, 2020, 卷号: 89, 页码: 233-237
Authors:  Zhang, Yao;  Yin, Shuang;  Zhang, Bingyang;  Bi, Jingxiu;  Liu, Yongdong;  Su, Zhiguo
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Virus-like particle (VLP)  Hepatitis B virus core antigen (HBc)  Inclusion body  Assembly  Sodium dodecyl sulfate (SDS)  2-methyl-2, 4-pentanediol (MPD)  
Enhanced multi-lineage differentiation of human mesenchymal stem/stromal cells within poly(N-isopropylacrylamide-acrylic acid) microgel-formed three-dimensional constructs 期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2018, 卷号: 6, 期号: 12, 页码: 1799-1814
Authors:  Zhang, Jiabin;  Yun, Seonho;  Bi, Jingxiu;  Dai, Sheng;  Du, Yuguang;  Zannettino, Andrew C. W.;  Zhang, Hu
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Prompt and Robust Humoral Immunity Elicited by a Conjugated Chimeric Malaria Antigen with a Truncated Flagellin 期刊论文
BIOCONJUGATE CHEMISTRY, 2018, 卷号: 29, 期号: 3, 页码: 761-770
Authors:  Guo, Fangxia;  Liu, Yongdong;  Zhang, Chun;  Wang, Qi;  Wang, Lianyan;  Gao, Yuhui;  Bi, Jingxiu;  Wang, Heng;  Su, Zhiguo
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Albumin Binding Domain Fusing R/K-X-X-R/K Sequence for Enhancing Tumor Delivery of Doxorubicin 期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 11, 页码: 3739-3749
Authors:  Liu, Liping;  Zhang, Chun;  Li, Zenglan;  Wang, Chunyue;  Bi, Jingxiu;  Yin, Shuang;  Wang, Qi;  Yu, Rong;  Liu, Yongdong;  Su, Zhiguo
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Albumin Binding Domain  Rgdk  Rparpar  Doxorubicin  Peptide-drug Conjugate  
A galactosamine-mediated drug delivery carrier for targeted liver cancer therapy 期刊论文
PHARMACOLOGICAL RESEARCH, 2011, 卷号: 64, 期号: 4, 页码: 410-419
Authors:  Shen, Zheyu;  Wei, Wei;  Tanaka, Hideyuki;  Kohama, Kazuhiro;  Ma, Guanghui;  Dobashi, Toshiaki;  Maki, Yasuyuki;  Wang, Honghui;  Bi, Jingxiu;  Dai, Sheng;  Bi, JX
Adobe PDF(710Kb)  |  Favorite  |  View/Download:182/1  |  Submit date:2013/10/30
Galactosamine  Drug Delivery Carrier  Targeted Therapy  Liver Cancer  
Regulation of protein multipoint adsorption on ion-exchange adsorbent and its application to the purification of macromolecules 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2010, 卷号: 74, 期号: 2, 页码: 257-263
Authors:  Huang, Yongdong;  Bi, Jingxiu;  Zhao, Lan;  Ma, Guanghui;  Su, Zhiguo;  Su, ZG
Adobe PDF(613Kb)  |  Favorite  |  View/Download:172/0  |  Submit date:2013/11/12
Multipoint Adsorption  Ligand Density  Steric Mass-action Model  Bovine Serum Albumin  Hepatitis b Surface Antigen  Macromolecule