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Extending Half Life of H-Ferritin Nanoparticle by Fusing Albumin Binding Domain for Doxorubicin Encapsulation 期刊论文
BIOMACROMOLECULES, 2018, 卷号: 19, 期号: 3, 页码: 773-781
Authors:  Wang, Chunyue;  Zhang, Chun;  Li, Zenglan;  Yin, Shuang;  Wang, Qi;  Guo, Fangxia;  Zhang, Yao;  Yu, Rong;  Liu, Yongdong;  Su, Zhiguo
Favorite  |  View/Download:34/0  |  Submit date:2018/06/11
Prompt and Robust Humoral Immunity Elicited by a Conjugated Chimeric Malaria Antigen with a Truncated Flagellin 期刊论文
BIOCONJUGATE CHEMISTRY, 2018, 卷号: 29, 期号: 3, 页码: 761-770
Authors:  Guo, Fangxia;  Liu, Yongdong;  Zhang, Chun;  Wang, Qi;  Wang, Lianyan;  Gao, Yuhui;  Bi, Jingxiu;  Wang, Heng;  Su, Zhiguo
Favorite  |  View/Download:37/0  |  Submit date:2018/06/11
Stabilization of a chimeric malaria antigen in separation and purification through efficient inhibition of protease activity by imidazole 期刊论文
PROCESS BIOCHEMISTRY, 2018, 卷号: 65, 页码: 213-219
Authors:  Guo, Fangxia;  Liu, Yongdong;  Zhang, Chun;  Wang, Qi;  Gao, Yuhui;  Deng, Weiwei;  Wang, Heng;  Su, Zhiguo
Favorite  |  View/Download:30/0  |  Submit date:2018/06/11
Multi-epitope  Malaria Antigen  Purification  Degradation  Imidazole  
Novel Bioconjugation Strategy Using Elevated Hydrostatic Pressure: A Case Study for the Site-Specific Attachment of Polyethylene Glycol (PEGylation) of Recombinant Human Ciliary Neurotrophic Factor 期刊论文
BIOCONJUGATE CHEMISTRY, 2017, 卷号: 28, 期号: 11, 页码: 2841-2848
Authors:  Wang, Qi;  Zhang, Chun;  Guo, Fangxia;  Li, Zenglan;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(4479Kb)  |  Favorite  |  View/Download:28/0  |  Submit date:2017/12/20
Oxidized catechol-derived poly (ethylene glycol) for thiol-specific conjugation 期刊论文
REACTIVE & FUNCTIONAL POLYMERS, 2017, 卷号: 117, 页码: 97-105
Authors:  Xu, Longfu;  Zhang, Chun;  Wang, Qi;  Guo, Fangxia;  Li, Zenglan;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(1098Kb)  |  Favorite  |  View/Download:41/0  |  Submit date:2017/09/06
Thiol-specific  Polyethylene Glycol  Pegylation Reagent  Catechol-derived Quinone  Protein Modification  
High hydrostatic pressure encapsulation of doxorubicin in ferritin nanocages with enhanced efficiency 期刊论文
JOURNAL OF BIOTECHNOLOGY, 2017, 卷号: 254, 页码: 34-42
Authors:  Wang, Qi;  Zhang, Chun;  Liu, Liping;  Lia, Zenglan;  Guo, Fangxia;  Li, Xiunan;  Luo, Jian;  Zhao, Dawei;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(1237Kb)  |  Favorite  |  View/Download:57/0  |  Submit date:2017/09/06
High Hydrostatic Pressure  Anticancer Drug  Human Ferritin  Doxorubicin  Encapsulation  Nanoparticle  
High hydrostatic pressure enables almost 100% refolding of recombinant human ciliary neurotrophic factor from inclusion bodies at high concentration 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2017, 卷号: 133, 页码: 152-159
Authors:  Wang, Qi;  Liu, Yongdong;  Zhang, Chun;  Guo, Fangxia;  Feng, Cui;  Li, Xiunan;  Shi, Hong;  Su, Zhiguo
Adobe PDF(2014Kb)  |  Favorite  |  View/Download:40/0  |  Submit date:2017/07/10
Rhcntf  High Hydrostatic Pressure  Inclusion Bodies  Hydrophobic Aggregation  Refolding  
新型疟疾嵌合抗原M312的纯化工艺及增强其免疫原性的研究 学位论文
博士: 中国科学院研究生院, 2017
Authors:  郭方霞
Adobe PDF(5256Kb)  |  Favorite  |  View/Download:15/0  |  Submit date:2019/03/29
疟疾疫苗,蛋白质降解,分离纯化,鞭毛蛋白,蛋白质偶联