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Traceable Nano-Biohybrid Complexes by One-Step Synthesis as CRISPR-Chem Vectors for Neurodegenerative Diseases Synergistic Treatment 期刊论文
ADVANCED MATERIALS, 2021, 页码: 10
Authors:  Shen, Jie;  Lu, Zhiguo;  Wang, Jianze;  Hao, Qiulian;  Ji, Weihong;  Wu, Yanyue;  Peng, Huan;  Zhao, Ruichen;  Yang, Jun;  Li, Yan;  Shi, Zhuyan;  Zhang, Xin
Favorite  |  View/Download:9/0  |  Submit date:2021/08/31
CRISPR  Cas9  CRISPR‐  chem vectors  neurodegenerative diseases synergistic treatment  one‐  step synthesis  traceable nano‐  biohybrid complexes  
Synaptic vesicle-inspired nanoparticles with spatiotemporally controlled release ability as a "nanoguard'' for synergistic treatment of synucleinopathies 期刊论文
MATERIALS HORIZONS, 2021, 卷号: 8, 期号: 4, 页码: 1199-1206
Authors:  Ji, Weihong;  Li, Yan;  Liu, Ruiyuan;  Lu, Zhiguo;  Liu, Linying;  Shi, Zhuyan;  Shen, Jie;  Zhang, Xin
Favorite  |  View/Download:7/0  |  Submit date:2021/08/31
Charge-switchable zwitterionic polycarboxybetaine particle as an intestinal permeation enhancer for efficient oral insulin delivery 期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 9, 页码: 4452-4466
Authors:  Li, Yan;  Ji, Weihong;  Peng, Huan;  Zhao, Ruichen;  Zhang, Tianlu;  Lu, Zhiguo;  Yang, Jun;  Liu, Ruiyuan;  Zhang, Xin
Favorite  |  View/Download:6/0  |  Submit date:2021/08/31
oral administration  charge-switchable  polycarboxybetaine  intestinal permeation enhancer  insulin  
pH-sensitive zwitterionic polycarboxybetaine as a potential non-viral vector for small interfering RNA delivery 期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 73, 页码: 45059-45066
Authors:  Peng, Huan;  Ji, Weihong;  Zhao, Ruichen;  Lu, Zhiguo;  Yang, Jun;  Li, Yan;  Zhang, Xin
Favorite  |  View/Download:16/0  |  Submit date:2021/03/29
Targeted exosome coating gene-chem nanocomplex as "nanoscavenger" for clearing alpha-synuclein and immune activation of Parkinson's disease 期刊论文
SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 50, 页码: 11
Authors:  Liu, Linying;  Li, Yan;  Peng, Huan;  Liu, Ruiyuan;  Ji, Weihong;  Shi, Zhuyan;  Shen, Jie;  Ma, Guanghui;  Zhang, Xin
Favorite  |  View/Download:14/0  |  Submit date:2021/03/29
Strategies and materials of SMARTnon-viral vectors: Overcoming the barriers for brain gene therapy 期刊论文
NANO TODAY, 2020, 卷号: 35, 页码: 22
Authors:  Li, Yan;  Liu, Linying;  Ji, Weihong;  Peng, Huang;  Zhao, Ruichen;  Zhang, Xin
Favorite  |  View/Download:14/0  |  Submit date:2021/03/29
Brain gene therapy  Non-viral vectors  Blood-brain barrier  Endosome trapping  Real-time non-invasive monitoring  
Exosome: a significant nano-scale drug delivery carrier 期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2020, 卷号: 8, 期号: 34, 页码: 7591-7608
Authors:  Peng, Huan;  Ji, Weihong;  Zhao, Ruichen;  Yang, Jun;  Lu, Zhiguo;  Li, Yan;  Zhang, Xin
Favorite  |  View/Download:27/0  |  Submit date:2020/10/30
A Reactive Oxygen Species-Responsive Poly(amino acids) Nanoparticle Loading Doxorubicin for Glioblastoma Multiforme Treatment 期刊论文
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2020, 卷号: 16, 期号: 6, 页码: 931-940
Authors:  Shi, Zhuyan;  Yang, Jun;  Liu, Linying;  Lu, Zhiguo;  Ji, Weihong;  Shen, Jie;  Zhang, Xin
Adobe PDF(8907Kb)  |  Favorite  |  View/Download:21/0  |  Submit date:2021/03/29
Poly(Amino Acids)  Drug Delivery  Ros-responsive Release  Doxorubicin  Glioblastoma Multiforme  
An "Amyloid-beta Cleaner" for the Treatment of Alzheimer's Disease by Normalizing Microglial Dysfunction 期刊论文
ADVANCED SCIENCE, 2019, 页码: 12
Authors:  Liu, Ruiyuan;  Yang, Jun;  Liu, Linying;  Lu, Zhiguo;  Shi, Zhuyan;  Ji, Weihong;  Shen, Jie;  Zhang, Xin
Adobe PDF(2682Kb)  |  Favorite  |  View/Download:57/0  |  Submit date:2020/03/24
Alzheimer's Disease  a Beta  Microglia  Neuroinflammation  Phagocytosis  
Switchable nanoparticle for programmed gene-chem delivery with enhanced neuronal recovery and CT imaging for neurodegenerative disease treatment 期刊论文
MATERIALS HORIZONS, 2019, 卷号: 6, 期号: 9, 页码: 1923-1929
Authors:  Liu, Linying;  Li, Yan;  Liu, Ruiyuan;  Shen, Qi;  Li, Yanhui;  Shi, Zhuyan;  Shen, Jie;  Ji, Weihong;  Zhang, Xin
Favorite  |  View/Download:77/0  |  Submit date:2019/12/02