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Extending Half Life of H-Ferritin Nanoparticle by Fusing Albumin Binding Domain for Doxorubicin Encapsulation 期刊论文
BIOMACROMOLECULES, 2018, 卷号: 19, 期号: 3, 页码: 773-781
Authors:  Wang, Chunyue;  Zhang, Chun;  Li, Zenglan;  Yin, Shuang;  Wang, Qi;  Guo, Fangxia;  Zhang, Yao;  Yu, Rong;  Liu, Yongdong;  Su, Zhiguo
Favorite  |  View/Download:73/0  |  Submit date:2018/06/11
Albumin Binding Domain Fusing R/K-X-X-R/K Sequence for Enhancing Tumor Delivery of Doxorubicin 期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 11, 页码: 3739-3749
Authors:  Liu, Liping;  Zhang, Chun;  Li, Zenglan;  Wang, Chunyue;  Bi, Jingxiu;  Yin, Shuang;  Wang, Qi;  Yu, Rong;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(6197Kb)  |  Favorite  |  View/Download:58/0  |  Submit date:2017/12/20
Albumin Binding Domain  Rgdk  Rparpar  Doxorubicin  Peptide-drug Conjugate  
Novel Bioconjugation Strategy Using Elevated Hydrostatic Pressure: A Case Study for the Site-Specific Attachment of Polyethylene Glycol (PEGylation) of Recombinant Human Ciliary Neurotrophic Factor 期刊论文
BIOCONJUGATE CHEMISTRY, 2017, 卷号: 28, 期号: 11, 页码: 2841-2848
Authors:  Wang, Qi;  Zhang, Chun;  Guo, Fangxia;  Li, Zenglan;  Liu, Yongdong;  Su, Zhiguo
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Prevention of aggregate formation through mechanism analysis in refolding of recombinant pertactin from Escherichia coli 期刊论文
PROCESS BIOCHEMISTRY, 2017, 卷号: 62, 期号: 00, 页码: 80-90
Authors:  Li, Zenglan;  Zhang, Chun;  Zhang, Yan;  Liu, Yongdong;  Li, Xiunan;  Ma, Guanghui;  Luo, Jim;  Su, Zhiguo
Adobe PDF(1328Kb)  |  Favorite  |  View/Download:34/0  |  Submit date:2018/01/19
Recombinant Pertactin  Refolding  Aggregates  Dilution  
Development of long-acting ciliary neurotrophic factor by site-specific conjugation with different-sized polyethylene glycols and transferrin 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017, 卷号: 529, 期号: 1-2, 页码: 275-284
Authors:  Zhang, Chun;  Yu, Rong;  Li, Zenglan;  Feng, Cui;  Wang, Qi;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(2220Kb)  |  Favorite  |  View/Download:67/0  |  Submit date:2017/11/27
Pegylation  Transferrin Coupling  Long-acting  Ciliary Neurotrophic Factor  Anti-obese  
Oxidized catechol-derived poly (ethylene glycol) for thiol-specific conjugation 期刊论文
REACTIVE & FUNCTIONAL POLYMERS, 2017, 卷号: 117, 页码: 97-105
Authors:  Xu, Longfu;  Zhang, Chun;  Wang, Qi;  Guo, Fangxia;  Li, Zenglan;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(1098Kb)  |  Favorite  |  View/Download:72/0  |  Submit date:2017/09/06
Thiol-specific  Polyethylene Glycol  Pegylation Reagent  Catechol-derived Quinone  Protein Modification  
High hydrostatic pressure encapsulation of doxorubicin in ferritin nanocages with enhanced efficiency 期刊论文
JOURNAL OF BIOTECHNOLOGY, 2017, 卷号: 254, 页码: 34-42
Authors:  Wang, Qi;  Zhang, Chun;  Liu, Liping;  Lia, Zenglan;  Guo, Fangxia;  Li, Xiunan;  Luo, Jian;  Zhao, Dawei;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(1237Kb)  |  Favorite  |  View/Download:86/0  |  Submit date:2017/09/06
High Hydrostatic Pressure  Anticancer Drug  Human Ferritin  Doxorubicin  Encapsulation  Nanoparticle  
Identification, characterization, and stabilization of the deamidation degradation of recombinant human tumor necrosis factor-alpha 期刊论文
PROCESS BIOCHEMISTRY, 2017, 卷号: 53, 页码: 216-223
Authors:  Yin, Shuang;  Zhang, Chun;  Li, Zenglan;  Wang, Qi;  Shi, Hong;  Yu, Rong;  Liu, Yongdong;  Su, Zhiguo
Adobe PDF(1796Kb)  |  Favorite  |  View/Download:78/0  |  Submit date:2017/04/17
Deamidation  Tumor Necrosis Factor-alpha  Lc-ms/ms  Polyol  Purification  
蛋白质纯化技术研究进展 期刊论文
现代生物医学进展, 2017, 卷号: 17, 期号: 32, 页码: 6389-6392+6223
Authors:  王启迪;  罗坚;  全灿;  周俊波;  李增兰
Adobe PDF(210Kb)  |  Favorite  |  View/Download:30/0  |  Submit date:2018/09/05
蛋白质  纯化  层析  非对称流场流分离  
百日咳粘着素的纯化和偶联:从分子结构到过程设计 学位论文
博士: 中国科学院研究生院, 2017
Authors:  李增兰
Adobe PDF(6815Kb)  |  Favorite  |  View/Download:14/0  |  Submit date:2019/03/29
组分疫苗,百日咳粘着素,纯化,复性,偶联