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A biomimetic VLP influenza vaccine with interior NP/exterior M2e antigens constructed through a temperature shift-based encapsulation strategy 期刊论文
VACCINE, 2020, 卷号: 38, 期号: 38, 页码: 5987-5996
Authors:  Wei, Jiangxue;  Li, Zhengjun;  Yang, Yanli;  Ma, Xiaowei;  An, Wenqi;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
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Influenza Vaccine  Virus Like-particles  Biomimetic  Nucleoprotein  M2e  
An Apoferritin-Hemagglutinin Conjugate Vaccine with Encapsulated Nucleoprotein Antigen Peptide from Influenza Virus Confers Enhanced Cross Protection 期刊论文
BIOCONJUGATE CHEMISTRY, 2020, 卷号: 31, 期号: 8, 页码: 1948-1959
Authors:  Wei, Jiangxue;  Li, Zhengjun;  Yang, Yanli;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
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A Novel Particulate Delivery System Based on Antigen-Zn2+ Coordination Interactions Enhances Stability and Cellular Immune Response of Inactivated Foot and Mouth Disease Virus Shuai 期刊论文
MOLECULAR PHARMACEUTICS, 2020, 卷号: 17, 期号: 8, 页码: 2952-2963
Authors:  Li, Shuai;  Yang, Yanli;  Lin, Xuan;  Li, Zhengjun;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
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Chitosan Particles  Coordination Binding  Foot And Mouth Disease Virus  Thermal Stability  Cellular Immunity  
Boron-based nanosheets for combined cancer photothermal and photodynamic therapy 期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2020, 卷号: 8, 期号: 21, 页码: 4609-4619
Authors:  Kang, Yong;  Ji, Xiaoyuan;  Li, Zhengjun;  Su, Zhiguo;  Zhang, Songping
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Mechanism of bio-macromolecule denaturation on solid-liquid surface of ion-exchange chromatographic media - A case study for inactivated foot-and-mouth disease virus 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1142, 页码: 10
Authors:  Yang, Yanli;  Song, Yanmin;  Lin, Xuan;  Li, Shuai;  Li, Zhengjun;  Zhao, Qizu;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
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Differential scanning calorimetry  Solid-liquid interface  Ion exchange chromatography  Foot-and-mouth disease virus  Dissociation  Stability  
Biocompatible cationic solid lipid nanoparticles as adjuvants effectively improve humoral and T cell immune response of foot and mouth disease vaccines 期刊论文
VACCINE, 2020, 卷号: 38, 期号: 11, 页码: 2478-2486
Authors:  Li, Shuai;  Yang, Yanli;  Lin, Xuan;  Li, Zhengjun;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
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Cationic Solid Lipid Nanoparticles  Foot And Mouth Disease Virus  Cellular Immunity  Adjuvant  Vaccine  
Development of meningococcal polysaccharide conjugate vaccine that can elicit long-lasting and strong cellular immune response with hepatitis B core antigen virus-like particles as a novel carrier protein 期刊论文
VACCINE, 2019, 卷号: 37, 期号: 7, 页码: 956-964
Authors:  Xu, Lingling;  Li, Zhengjun;  Su, Zhiguo;  Yang, Yanli;  Ma, Guanghui;  Yu, Rong;  Zhang, Songping
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Neisseria meningitidis  Conjugate vaccine  Hepatitis B core antigen  Virus-like particles  
A two-step heat treatment of cell disruption supernatant enables efficient removal of host cell proteins before chromatographic purification of HBc particles 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1581, 页码: 71-79
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Liu, Lili;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
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Hepatitis b Core Protein  Thermal Stability  Particles  Purification  Host Cell Protein  Chromatography  
Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2018, 卷号: 140, 页码: 157-167
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Ma, Xiaowei;  Hou, Baidong;  An, Wenqi;  Hua, Zhaolin;  Zhan, Jingjing;  Li, Yao;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
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Hbc-vlp  Hydrophobic Interaction Chromatography  Surface Hydrophobicity Properties  Rational Design  Vaccine Candidates  
以乙肝核心抗原病毒样颗粒为新型载体蛋白制备流脑多糖结合疫苗 期刊论文
华西药学杂志, 2018, 卷号: 33, 期号: 06, 页码: 463-467
Authors:  胥玲玲;  李正军;  苏志国;  杨延丽;  余蓉;  郑永祥;  张松平
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流行性脑脊髓膜炎  C群脑膜炎多糖  乙肝核心抗原  病毒样颗粒  结合疫苗  载体蛋白  免疫活性