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A novel rapid modularized hepatitis B core virus-like particle-based platform for personalized cancer vaccine preparation via fixed-point coupling 期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 28, 页码: 13
Authors:  Ji, Mei;  Zhu, Jie;  Xie, Xi-xiu;  Liu, Dong-qun;  Wang, Bin;  Yu, Zhuo;  Liu, Rui-tian
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Hepatitis b Core Protein  Virus-like Particle (Vlp)  Personalized Cancer Vaccine  Spycatcher/spytag  t Cell Epitope  
Engineered hepatitis B core virus-like particle carrier for precise and personalized Alzheimer's disease vaccine preparation via fixed-point coupling 期刊论文
APPLIED MATERIALS TODAY, 2020, 卷号: 19, 页码: 16
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Lu, Shuai;  Zhang, Ling-xiao;  Huang, Ya-ru;  Liu, Rui-tian
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Alzheimer's disease  Virus-like particles (VLPs)  B cell epitope peptide  SpyCatcher/SpyTag  Th2-type immune response  
A Conditionally Releasable "Do not Eat Me" CD47 Signal Facilitates Microglia-Targeted Drug Delivery for the Treatment of Alzheimer's Disease 期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 10
Authors:  Zhang, Lun;  Liu, Xiao-ge;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Ling-xiao;  Zhu, Jie;  Lu, Shuai;  Liu, Rui-tian
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Alzheimer's Disease  Brain Delivery  Cd47  Microglia  Ripk1  
Multifunctional Superparamagnetic Iron Oxide Nanoparticles Conjugated with A beta Oligomer-Specific scFv Antibody and Class A Scavenger Receptor Activator Show Early Diagnostic Potentials for Alzheimer's Disease 期刊论文
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2020, 卷号: 15, 页码: 4919-4932
Authors:  Liu, Xiao-Ge;  Zhang, Lun;  Lu, Shuai;  Liu, Dong-Qun;  Zhang, Ling-Xiao;  Yu, Xiao-Lin;  Liu, Rui-Tian
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magnetic resonance imaging  diagnosis  Alzheimer 's disease  beta-amyloid  oligomer  class A scavenger receptor  
基于酿酒酵母载体的肿瘤疫苗的研究 学位论文
博士: 中国科学院大学, 2019
Authors:  刘栋群
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肿瘤疫苗  酿酒酵母  免疫调节  仿生设计  
ScFv-conjugated superparamagnetic iron oxide nanoparticles for MRI-based diagnosis in transgenic mouse models of Parkinson's and Huntington's diseases 期刊论文
BRAIN RESEARCH, 2019, 卷号: 1707, 页码: 141-153
Authors:  Liu, Xiao-ge;  Lu, Shuai;  Liu, Dong-qun;  Zhang, Lun;  Zhang, Ling-xiao;  Yu, Xiao-lin;  Liu, Rui-tian
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Magnetic resonance imaging  Diagnosis  Parkinson's disease  Huntington's disease  Amyloid oligomer  ScFv antibody  
Efficient co-delivery of neo-epitopes using dispersion-stable layered double hydroxide nanoparticles for enhanced melanoma immunotherapy 期刊论文
BIOMATERIALS, 2018, 卷号: 174, 页码: 54-66
Authors:  Zhang, Ling-xiao;  Xie, Xi-xiu;  Liu, Dong-qun;  Xu, Zhi Ping;  Liu, Rui-tian
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Therapeutic Cancer Vaccine  Layered Double Hydroxides  Colloidal Stability  Personalized Immunotherapy  Melanoma  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
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Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
An indoleamine 2, 3-dioxygenase siRNA nanoparticle-coated and Trp2-displayed recombinant yeast vaccine inhibits melanoma tumor growth in mice 期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 273, 页码: 1-12
Authors:  Liu, Dong-qun;  Lu, Shuai;  Zhang, Ling-xiao;  Ji, Mei;  Liu, Shu-ying;  Wang, Shao-wei;  Liu, Rui-tian
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Small Interfering Rna (siRna)  Indoleamine 2  Nanoparticle  3-dioxygenase (Ido)  Tyrosinase-related Protein 2 (Trp2)  Saccharomyces Cerevisiae  Melanoma Tumor  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
Authors:  Ji, M;  Xie, XX;  Liu, DQ;  Yu, XL;  Zhang, Y;  Zhang, LX;  Wang, SW;  Huang, YR;  Liu, RT;  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
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Alzheimer's Disease  Virus-like Particles  Frontotemporal Dementia  In-vivo  Hepatitis b Core Protein  Neurofibrillary Degeneration  Truncated Tau  Corticobasal Degeneration  Neurofibrillary Tangles  Structural Determinants  Virus-like Particles (Vlps)  Truncated Tau  Vaccine  Immunotherapy  Protein  Pathology  Tauopathy