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The immunodominant and neutralization linear epitopes for SARS-CoV-2 期刊论文
CELL REPORTS, 2021, 卷号: 34, 期号: 4, 页码: 12
Authors:  Lu, Shuai;  Xie, Xi-xiu;  Zhao, Lei;  Wang, Bin;  Zhu, Jie;  Yang, Ting-rui;  Yang, Guang-wen;  Ji, Mei;  Lv, Cui-ping;  Xue, Jian;  Dai, Er-hei;  Fu, Xi-ming;  Liu, Dong-qun;  Zhang, Lun;  Hou, Sheng-jie;  Yu, Xiao-lin;  Wang, Yu-ling;  Gao, Hui-xia;  Shi, Xue-han;  Ke, Chang-wen;  Ke, Bi-xia;  Jiang, Chun-guo;  Liu, Rui-tian
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Superparamagnetic iron oxide nanoparticles conjugated with Aβ oligomer-specific scFv antibody and class A scavenger receptor activator show therapeutic potentials for Alzheimer’s Disease 期刊论文
Journal of Nanobiotechnology, 2020, 卷号: 18, 期号: 1
Authors:  Liu,Xiao-ge;  Zhang,Lun;  Lu,Shuai;  Liu,Dong-qun;  Huang,Ya-ru;  Zhu,Jie;  Zhou,Wei-wei;  Yu,Xiao-lin;  Liu,Rui-tian
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Alzheimer’s disease  β-Amyloid  Oligomer  Class A scavenger receptor  Therapy  
Superparamagnetic iron oxide nanoparticles conjugated with A beta oligomer-specific scFv antibody and class A scavenger receptor activator show therapeutic potentials for Alzheimer's Disease 期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2020, 卷号: 18, 期号: 1, 页码: 13
Authors:  Liu, Xiao-ge;  Zhang, Lun;  Lu, Shuai;  Liu, Dong-qun;  Huang, Ya-ru;  Zhu, Jie;  Zhou, Wei-wei;  Yu, Xiao-lin;  Liu, Rui-tian
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Alzheimer's disease  beta-Amyloid  Oligomer  Class A scavenger receptor  Therapy  
Yeast-Based A beta 1-15 Vaccine Elicits Strong Immunogenicity and Attenuates Neuropathology and Cognitive Deficits in Alzheimer's Disease Transgenic Mice 期刊论文
VACCINES, 2020, 卷号: 8, 期号: 3, 页码: 13
Authors:  Liu, Dong-qun;  Lu, Shuai;  Zhang, Lun;  Huang, Ya-ru;  Ji, Mei;  Sun, Xiao-ying;  Liu, Xiao-ge;  Liu, Rui-tian
Favorite  |  View/Download:8/0  |  Submit date:2021/03/29
Alzheimer's disease  beta-amyloid  active immunotherapy  yeast  vaccine  
A novel rapid modularized hepatitis B core virus-like particle-based platform for personalized cancer vaccine preparation via fixed-point coupling 期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 28, 页码: 13
Authors:  Ji, Mei;  Zhu, Jie;  Xie, Xi-xiu;  Liu, Dong-qun;  Wang, Bin;  Yu, Zhuo;  Liu, Rui-tian
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Hepatitis b Core Protein  Virus-like Particle (Vlp)  Personalized Cancer Vaccine  Spycatcher/spytag  t Cell Epitope  
Engineered hepatitis B core virus-like particle carrier for precise and personalized Alzheimer's disease vaccine preparation via fixed-point coupling 期刊论文
APPLIED MATERIALS TODAY, 2020, 卷号: 19, 页码: 16
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Lu, Shuai;  Zhang, Ling-xiao;  Huang, Ya-ru;  Liu, Rui-tian
Favorite  |  View/Download:31/0  |  Submit date:2020/09/22
Alzheimer's disease  Virus-like particles (VLPs)  B cell epitope peptide  SpyCatcher/SpyTag  Th2-type immune response  
A Conditionally Releasable "Do not Eat Me" CD47 Signal Facilitates Microglia-Targeted Drug Delivery for the Treatment of Alzheimer's Disease 期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 10
Authors:  Zhang, Lun;  Liu, Xiao-ge;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Ling-xiao;  Zhu, Jie;  Lu, Shuai;  Liu, Rui-tian
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Alzheimer's Disease  Brain Delivery  Cd47  Microglia  Ripk1  
Multifunctional Superparamagnetic Iron Oxide Nanoparticles Conjugated with A beta Oligomer-Specific scFv Antibody and Class A Scavenger Receptor Activator Show Early Diagnostic Potentials for Alzheimer's Disease 期刊论文
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2020, 卷号: 15, 页码: 4919-4932
Authors:  Liu, Xiao-Ge;  Zhang, Lun;  Lu, Shuai;  Liu, Dong-Qun;  Zhang, Ling-Xiao;  Yu, Xiao-Lin;  Liu, Rui-Tian
Favorite  |  View/Download:23/0  |  Submit date:2020/09/22
magnetic resonance imaging  diagnosis  Alzheimer 's disease  beta-amyloid  oligomer  class A scavenger receptor  
基于酿酒酵母载体的肿瘤疫苗的研究 学位论文
博士: 中国科学院大学, 2019
Authors:  刘栋群
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肿瘤疫苗  酿酒酵母  免疫调节  仿生设计  
ScFv-conjugated superparamagnetic iron oxide nanoparticles for MRI-based diagnosis in transgenic mouse models of Parkinson's and Huntington's diseases 期刊论文
BRAIN RESEARCH, 2019, 卷号: 1707, 页码: 141-153
Authors:  Liu, Xiao-ge;  Lu, Shuai;  Liu, Dong-qun;  Zhang, Lun;  Zhang, Ling-xiao;  Yu, Xiao-lin;  Liu, Rui-tian
Favorite  |  View/Download:94/0  |  Submit date:2019/06/14
Magnetic resonance imaging  Diagnosis  Parkinson's disease  Huntington's disease  Amyloid oligomer  ScFv antibody