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Development of Multifunctional Clay-Based Nanomedicine for Elimination of Primary Invasive Breast Cancer and Prevention of Its Lung Metastasis and Distant Inoculation 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 39, 页码: 35566-35576
Authors:  Zhang, Ling-xiao;  Sun, Xia-mei;  Xu, Zhi Ping;  Liu, Rui-tian
Favorite  |  View/Download:6/0  |  Submit date:2019/12/02
layered double hydroxides  multifunctional nanomedicine  photothermal therapy  chemotherapy  cancer immunotherapy  
Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease 期刊论文
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
Authors:  Huang, Ya-ru;  Xie, Xi-xiu;  Ji, Mei;  Yu, Xiao-lin;  Zhu, Jie;  Zhang, Ling-xiao;  Liu, Xiao-ge;  Wei, Chen;  Li, Gang;  Liu, Rui-tian
Favorite  |  View/Download:50/0  |  Submit date:2019/04/03
Parkinson's disease  alpha-Synuclein  Naturally occurring autoantibodies  A53T mice  WIG  
ScFv-conjugated superparamagnetic iron oxide nanoparticles for MRI-based diagnosis in transgenic mouse models of Parkinson's and Huntington's diseases 期刊论文
BRAIN RESEARCH, 2019, 卷号: 1707, 页码: 141-153
Authors:  Liu, Xiao-ge;  Lu, Shuai;  Liu, Dong-qun;  Zhang, Lun;  Zhang, Ling-xiao;  Yu, Xiao-lin;  Liu, Rui-tian
Favorite  |  View/Download:48/0  |  Submit date:2019/06/14
Magnetic resonance imaging  Diagnosis  Parkinson's disease  Huntington's disease  Amyloid oligomer  ScFv antibody  
Resveratrol Rescues Tau-Induced Cognitive Deficits and Neuropathology in a Mouse Model of Tauopathy 期刊论文
CURRENT ALZHEIMER RESEARCH, 2019, 卷号: 16, 期号: 8, 页码: 710-722
Authors:  Sun, Xiao-Ying;  Dong, Quan-Xiu;  Zhu, Jie;  Sun, Xun;  Zhang, Li-Fan;  Qiu, Mandy;  Yu, Xiao-Lin;  Liu, Rui-Tian
Favorite  |  View/Download:5/0  |  Submit date:2019/12/02
Resveratrol  Alzheimer's disease  tau  oligomer  neuroinflammation  synapse loss  
Resveratrol alleviates motor and cognitive deficits and neuropathology in the A53T-synuclein mouse model of Parkinson's disease 期刊论文
FOOD & FUNCTION, 2018, 卷号: 9, 期号: 12, 页码: 6415-6427
Authors:  Zhang, Li-fan;  Yu, Xiao-lin;  Ji, Mei;  Liu, Shu-ying;  Wu, Xiao-ling;  Wang, Yu-jiong;  Liu, Rui-tian
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Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-kappa B signaling pathway 期刊论文
BRAIN RESEARCH, 2018, 卷号: 1697, 页码: 21-33
Authors:  Liu, Shu-ying;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Xiang-meng;  Zhang, Yue;  Dong, Quan-xiu;  Ma, Shan;  Liu, Rui-tian
Adobe PDF(4079Kb)  |  Favorite  |  View/Download:50/0  |  Submit date:2018/10/11
Huntington's Disease  Polyglutamine  Intravenous Immunoglobulin  Huntingtin Protein  
Efficient co-delivery of neo-epitopes using dispersion-stable layered double hydroxide nanoparticles for enhanced melanoma immunotherapy 期刊论文
BIOMATERIALS, 2018, 卷号: 174, 页码: 54-66
Authors:  Zhang, Ling-xiao;  Xie, Xi-xiu;  Liu, Dong-qun;  Xu, Zhi Ping;  Liu, Rui-tian
Adobe PDF(3177Kb)  |  Favorite  |  View/Download:90/0  |  Submit date:2018/09/04
Therapeutic Cancer Vaccine  Layered Double Hydroxides  Colloidal Stability  Personalized Immunotherapy  Melanoma  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:72/0  |  Submit date:2018/07/17
Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
An indoleamine 2, 3-dioxygenase siRNA nanoparticle-coated and Trp2-displayed recombinant yeast vaccine inhibits melanoma tumor growth in mice 期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 273, 页码: 1-12
Authors:  Liu, Dong-qun;  Lu, Shuai;  Zhang, Ling-xiao;  Ji, Mei;  Liu, Shu-ying;  Wang, Shao-wei;  Liu, Rui-tian
Adobe PDF(1633Kb)  |  Favorite  |  View/Download:66/0  |  Submit date:2018/06/11
Small Interfering Rna (siRna)  Indoleamine 2  Nanoparticle  3-dioxygenase (Ido)  Tyrosinase-related Protein 2 (Trp2)  Saccharomyces Cerevisiae  Melanoma Tumor  
Intravenous immunoglobulin improves glucose control and beta-cell function in human IAPP transgenic mice by attenuating islet inflammation and reducing IAPP oligomers 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 54, 页码: 145-152
Authors:  Zhang, Yue;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Shu-ying;  Liu, Xiang-meng;  Dong, Quan-xiu;  Chai, Jia-qian;  Liu, Rui-tian
Favorite  |  View/Download:55/0  |  Submit date:2018/06/11
Type 2 Diabetes Mellitus  Intravenous Immunoglobulin  Islet Amyloid Polypeptide  Islet Inflammation  Toxic Oligomer