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A triply modified human adult hemoglobin with low oxygen affinity, rapid autoxidation and high tetramer stability 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 159, 页码: 236-242
Authors:  Yan, Wenying;  Shen, Lijuan;  Yu, Weili;  Wang, Ying;  Wang, Quan;  You, Guoxing;  Zhao, Lian;  Zhou, Hong;  Hu, Tao
Adobe PDF(1013Kb)  |  Favorite  |  View/Download:22/0  |  Submit date:2020/10/30
Hemoglobin  Oxygen Affinity, Autoxidation  
Conjugation of beta-Glucan with the Hydrazone and Disulfide Linkers Markedly Improves the Immunogenicity of Zika Virus E Protein 期刊论文
MOLECULAR PHARMACEUTICS, 2020, 卷号: 17, 期号: 6, 页码: 1933-1944
Authors:  Qi, Jinming;  Yin, Ying;  Yu, Weili;  Shen, Lijuan;  Xu, Junjie;  Hu, Tao
Favorite  |  View/Download:40/0  |  Submit date:2020/07/23
Zika virus  beta-glucan  E protein  adjuvant  hydrazine  disulfide  
Self-conjugated protective antigen elicits strong and durable protective antibody response against anthrax 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 137, 页码: 790-800
Authors:  Yin, Ying;  Yu, Weili;  Li, Yujie;  Liu, Kun;  Zai, Xiaodong;  Zhang, Jun;  Fu, Ling;  Hu, Tao;  Xu, Junjie;  Chen, Wei
Favorite  |  View/Download:66/0  |  Submit date:2019/10/18
Antigen delivery system  Anthrax  Self-conjugation  Polyethylene glycol  
Conjugation of staphylokinase with the arabinogalactan-PEG conjugate: Study on the immunogenicity, in vitro bioactivity and pharmacokinetics 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 131, 页码: 896-904
Authors:  Qi, Fangbing;  Qi, Jinming;  Hu, Chunyang;  Shen, Lijuan;  Yu, Weili;  Hu, Tao
Favorite  |  View/Download:80/0  |  Submit date:2019/06/14
Staphylokinase  Arabinogalactan  Immunogenicity  Pharmacokinetic  PEG linker  in vitro activity  
An effective immobilized haloalkane dehalogenase DhaA from Rhodococcus rhodochrous by adsorption, crosslink and PEGylation on meso-cellular foam 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 125, 页码: 1016-1023
Authors:  Zheng, He;  Yu, Wei-Li;  Guo, Xuan;  Zhao, Yuan-Zhong;  Cui, Yan;  Hu, Tao;  Zhong, Jin-Yi
Adobe PDF(556Kb)  |  Favorite  |  View/Download:143/0  |  Submit date:2019/04/03
Haloalkane Dehalogenase  Meso-cellular Foam  Enzyme Immobilization  
Influence of polydopamine-mediated surface modification on oxygen-release capacity of haemoglobin-based oxygen carriers 期刊论文
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, 2018, 卷号: 46, 页码: 484-492
Authors:  Wang, Quan;  Zhang, Ruirui;  You, Guoxing;  Hu, Jilin;  Li, Penglong;  Wang, Ying;  Zhang, Jun;  Wu, Yan;  Zhao, Lian;  Zhou, Hong
Favorite  |  View/Download:97/0  |  Submit date:2019/04/03
Polydopamine  haemoglobin  surface modification  oxygen carriers  oxidative toxicity  
In vitro and in vivo investigation of the novel Dex-bHb as oxygen carriers 期刊论文
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, 2018, 卷号: 46, 页码: S133-S137
Authors:  Zhang, Jun;  Wang, Ying;  Zhang, Shan;  You, Guo-Xing;  Li, Peng-Long;  Wang, Quan;  Yu, Wei-Li;  Hu, Tao;  Zhou, Hong;  Zhao, Lian
Favorite  |  View/Download:83/0  |  Submit date:2019/06/14
HBOCs  Dex-bHb  blood compatibility  organ protection