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Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease 期刊论文
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
Authors:  Huang, Ya-ru;  Xie, Xi-xiu;  Ji, Mei;  Yu, Xiao-lin;  Zhu, Jie;  Zhang, Ling-xiao;  Liu, Xiao-ge;  Wei, Chen;  Li, Gang;  Liu, Rui-tian
Favorite  |  View/Download:33/0  |  Submit date:2019/04/03
Parkinson's disease  alpha-Synuclein  Naturally occurring autoantibodies  A53T mice  WIG  
Efficient co-delivery of neo-epitopes using dispersion-stable layered double hydroxide nanoparticles for enhanced melanoma immunotherapy 期刊论文
BIOMATERIALS, 2018, 卷号: 174, 页码: 54-66
Authors:  Zhang, Ling-xiao;  Xie, Xi-xiu;  Liu, Dong-qun;  Xu, Zhi Ping;  Liu, Rui-tian
Adobe PDF(3177Kb)  |  Favorite  |  View/Download:68/0  |  Submit date:2018/09/04
Therapeutic Cancer Vaccine  Layered Double Hydroxides  Colloidal Stability  Personalized Immunotherapy  Melanoma  
融合表达白细胞介素10与卵清蛋白重组腺病毒口服变应原疫苗的构建及鉴定 期刊论文
中华临床免疫和变态反应杂志, 2018, 2018, 卷号: 12, 期号: 03, 页码: 263-269
Authors:  马仕坤;  关剑;  王丹;  甄宏楠;  谢喜秀
Favorite  |  View/Download:12/0  |  Submit date:2019/06/17
白细胞介素10  变应原  重组腺病毒  口服疫苗  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Favorite  |  View/Download:59/0  |  Submit date:2018/07/17
Alzheimer's disease  Frontotemporal dementia  Hepatitis B core protein  Truncated tau  Neurofibrillary tangles  Virus-like particles (VLPs)  Vaccine  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
Authors:  Ji, M;  Xie, XX;  Liu, DQ;  Yu, XL;  Zhang, Y;  Zhang, LX;  Wang, SW;  Huang, YR;  Liu, RT;  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Favorite  |  View/Download:25/0  |  Submit date:2018/12/29
Alzheimer's disease  VIRUS-LIKE PARTICLES  Frontotemporal dementia  IN-VIVO  Hepatitis B core protein  NEUROFIBRILLARY DEGENERATION  Truncated tau  CORTICOBASAL DEGENERATION  Neurofibrillary tangles  STRUCTURAL DETERMINANTS  Virus-like particles (VLPs)  TRUNCATED TAU  Vaccine  IMMUNOTHERAPY  PROTEIN  PATHOLOGY  TAUOPATHY  
MgAl-layered double hydroxide nanoparticles co-delivering siIDO and Trp2 peptide effectively reduce IDO expression and induce cytotoxic T-lymphocyte responses against melanoma tumor in mice 期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2017, 卷号: 5, 期号: 31, 页码: 6266-6276
Authors:  Zhang, Ling-xiao;  Liu, Dong-qun;  Wang, Shao-wei;  Yu, Xiao-lin;  Ji, Mei;  Xie, Xi-xiu;  Liu, Shu-ying;  Liu, Rui-tian
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A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer’s disease 期刊论文
Alzheimer's Research & Therapy, 2017, 卷号: 9, 期号: 1
Authors:  Wang,Shao-wei;  Liu,Dong-qun;  Zhang,Ling-xiao;  Ji,Mei;  Zhang,Yang-xin;  Dong,Quan-xiu;  Liu,Shu-ying;  Xie,Xi-xiu;  Liu,Rui-tian
Adobe PDF(9258Kb)  |  Favorite  |  View/Download:52/0  |  Submit date:2018/07/17
Alzheimer’s Disease  Β-amyloid Oligomer  Mimotope  Saccharomyces Cerevisiae  Vaccine  
A vaccine with A beta oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer's disease 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2017, 卷号: 9
Authors:  Wang, Shao-wei;  Liu, Dong-qun;  Zhang, Ling-xiao;  Ji, Mei;  Zhang, Yang-xin;  Dong, Quan-xiu;  Liu, Shu-ying;  Xie, Xi-xiu;  Liu, Rui-tian
Adobe PDF(9258Kb)  |  Favorite  |  View/Download:107/0  |  Submit date:2017/09/06
Alzheimer's Disease  Beta-amyloid Oligomer  Mimotope  Saccharomyces Cerevisiae  Vaccine  
Naturally occurring autoantibodies against A beta oligomers exhibited more beneficial effects in the treatment of mouse model of Alzheimer's disease than intravenous immunoglobulin 期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 105, 期号: JUNE, 页码: 561-576
Authors:  Wang, Teng;  Xie, Xi-xiu;  Ji, Mei;  Wang, Shao-wei;  Zha, Jun;  Zhou, Wei-wei;  Yu, Xiao-lin;  Wei, Chen;  Ma, Shan;  Xi, Zhi-ying;  Pang, Guang-li;  Liu, Rui-tian
Adobe PDF(5810Kb)  |  Favorite  |  View/Download:79/0  |  Submit date:2016/07/15
Alzheimer's Disease  Beta-amyloid  Intravenous Immunoglobulin  Oligomers  Antibody  
天然Aβ寡聚体抗体的制备研究 期刊论文
四川大学学报(自然科学版), 2016, 期号: 3, 页码: "652-656"
Authors:  王腾;  季梅;  谢喜秀;  汪维云
Adobe PDF(523Kb)  |  Favorite  |  View/Download:32/0  |  Submit date:2017/05/31
阿尔茨海默症  淀粉样蛋白寡聚体  多克隆抗体