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Development of meningococcal polysaccharide conjugate vaccine that can elicit long-lasting and strong cellular immune response with hepatitis B core antigen virus-like particles as a novel carrier protein 期刊论文
VACCINE, 2019, 卷号: 37, 期号: 7, 页码: 956-964
Authors:  Xu, Lingling;  Li, Zhengjun;  Su, Zhiguo;  Yang, Yanli;  Ma, Guanghui;  Yu, Rong;  Zhang, Songping
Favorite  |  View/Download:43/0  |  Submit date:2019/04/03
Neisseria meningitidis  Conjugate vaccine  Hepatitis B core antigen  Virus-like particles  
Unique stabilizing mechanism provided by biocompatible choline-based ionic liquids for inhibiting dissociation of inactivated foot-and-mouth disease virus particles 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 24, 页码: 13933-13939
Authors:  Lin, Xuan;  Yang, Yanli;  Li, Shuai;  Song, Yanmin;  Ma, Guanghui;  Su, Zhiguo;  Zhang, Songping
Favorite  |  View/Download:38/0  |  Submit date:2019/06/14
A two-step heat treatment of cell disruption supernatant enables efficient removal of host cell proteins before chromatographic purification of HBc particles 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1581, 页码: 71-79
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Liu, Lili;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
Adobe PDF(2114Kb)  |  Favorite  |  View/Download:69/0  |  Submit date:2019/04/03
Hepatitis b Core Protein  Thermal Stability  Particles  Purification  Host Cell Protein  Chromatography  
Strong hydrophobicity enables efficient purification of HBc VLPs displaying various antigen epitopes through hydrophobic interaction chromatography 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2018, 卷号: 140, 页码: 157-167
Authors:  Li, Zhengjun;  Wei, Jiangxue;  Yang, Yanli;  Ma, Xiaowei;  Hou, Baidong;  An, Wenqi;  Hua, Zhaolin;  Zhan, Jingjing;  Li, Yao;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
Adobe PDF(2413Kb)  |  Favorite  |  View/Download:80/0  |  Submit date:2018/12/28
Hbc-vlp  Hydrophobic Interaction Chromatography  Surface Hydrophobicity Properties  Rational Design  Vaccine Candidates  
应用体积排阻色谱法测定口蹄疫灭活疫苗中的146S抗原含量 期刊论文
生物工程学报, 2018, 卷号: 34, 期号: 05, 页码: 676-684
Authors:  徐嫄;  邹兴启;  李翠;  朱元源;  何天慈;  杨延丽;  林旋;  宋艳民;  郑金来;  张松平;  赵启祖
Adobe PDF(1539Kb)  |  Favorite  |  View/Download:22/0  |  Submit date:2019/06/17
体积排阻色谱  口蹄疫  灭活疫苗  146s抗原  
以乙肝核心抗原病毒样颗粒为新型载体蛋白制备流脑多糖结合疫苗 期刊论文
华西药学杂志, 2018, 卷号: 33, 期号: 06, 页码: 463-467
Authors:  胥玲玲;  李正军;  苏志国;  杨延丽;  余蓉;  郑永祥;  张松平
Adobe PDF(1243Kb)  |  Favorite  |  View/Download:21/0  |  Submit date:2019/06/17
流行性脑脊髓膜炎  C群脑膜炎多糖  乙肝核心抗原  病毒样颗粒  结合疫苗  载体蛋白  免疫活性  
Denaturation of inactivated FMDV in ion exchange chromatography: Evidence by differential scanning calorimetry analysis 期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2017, 卷号: 124, 页码: 99-107
Authors:  Liang, Shanqin;  Yang, Yanli;  Sun, Lijing;  Zhao, Qizu;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
Adobe PDF(2010Kb)  |  Favorite  |  View/Download:95/0  |  Submit date:2017/08/14
Foot And Mouth Disease Virus  Ion Exchange Chromatography  Differential Scanning Calorimetry  Stability  Dissociation  
Stabilization study of inactivated foot and mouth disease virus vaccine by size-exclusion HPLC and differential scanning calorimetry 期刊论文
VACCINE, 2017, 卷号: 35, 期号: 18, 页码: 2413-2419
Authors:  Yang, Yanli;  Zhao, Qizu;  Li, Zhengjun;  Sun, Lijing;  Ma, Guanghui;  Zhang, Songping;  Su, Zhiguo
Adobe PDF(1469Kb)  |  Favorite  |  View/Download:82/0  |  Submit date:2017/09/06
Foot And Mouth Disease Virus  Thermal Stability  Dissociation  Stabilization  Excipient  
灭活病毒及病毒颗粒的结构表征和稳定性研究 学位论文
, 北京: 中国科学院研究生院, 2015
Authors:  杨延丽
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灭活病毒  病毒样颗粒  口蹄疫病毒  乙肝病毒表面抗原  稳定  
A hydrophobic interaction chromatography strategy for purification of inactivated foot-and-mouth disease virus 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2015, 卷号: 113, 期号: SEP, 页码: 23-29
Authors:  Li, Hao;  Yang, Yanli;  Zhang, Yan;  Zhang, Songping;  Zhao, Qizu;  Zhu, Yuanyuan;  Zou, Xingqi;  Yu, Mengran;  Ma, Guanghui;  Su, Zhiguo
Adobe PDF(1108Kb)  |  Favorite  |  View/Download:101/0  |  Submit date:2015/08/18
Foot-and-mouth Disease Virus  Hydrophobic Interaction Chromatography  Purification  Downstream Processing