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Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease 期刊论文
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
Authors:  Huang, Ya-ru;  Xie, Xi-xiu;  Ji, Mei;  Yu, Xiao-lin;  Zhu, Jie;  Zhang, Ling-xiao;  Liu, Xiao-ge;  Wei, Chen;  Li, Gang;  Liu, Rui-tian
Favorite  |  View/Download:45/0  |  Submit date:2019/04/03
Parkinson's disease  alpha-Synuclein  Naturally occurring autoantibodies  A53T mice  WIG  
ScFv-conjugated superparamagnetic iron oxide nanoparticles for MRI-based diagnosis in transgenic mouse models of Parkinson's and Huntington's diseases 期刊论文
BRAIN RESEARCH, 2019, 卷号: 1707, 页码: 141-153
Authors:  Liu, Xiao-ge;  Lu, Shuai;  Liu, Dong-qun;  Zhang, Lun;  Zhang, Ling-xiao;  Yu, Xiao-lin;  Liu, Rui-tian
Favorite  |  View/Download:41/0  |  Submit date:2019/06/14
Magnetic resonance imaging  Diagnosis  Parkinson's disease  Huntington's disease  Amyloid oligomer  ScFv antibody  
Resveratrol Rescues Tau-Induced Cognitive Deficits and Neuropathology in a Mouse Model of Tauopathy 期刊论文
CURRENT ALZHEIMER RESEARCH, 2019, 卷号: 16, 期号: 8, 页码: 710-722
Authors:  Sun, Xiao-Ying;  Dong, Quan-Xiu;  Zhu, Jie;  Sun, Xun;  Zhang, Li-Fan;  Qiu, Mandy;  Yu, Xiao-Lin;  Liu, Rui-Tian
Favorite  |  View/Download:0/0  |  Submit date:2019/12/02
Resveratrol  Alzheimer's disease  tau  oligomer  neuroinflammation  synapse loss  
多孔陶瓷材料力学特性的离散单元法定量模拟 期刊论文
中国科学物理学力学天文学, 2019, 卷号: 049, 期号: 006, 页码: 24
Authors:  周爽;  苏景林;  刘晓星;  安百钢;  喻寅;  贺红亮;  张泉;  冯勇进;  王晓宇
Favorite  |  View/Download:3/0  |  Submit date:2019/12/02
Resveratrol alleviates motor and cognitive deficits and neuropathology in the A53T-synuclein mouse model of Parkinson's disease 期刊论文
FOOD & FUNCTION, 2018, 卷号: 9, 期号: 12, 页码: 6415-6427
Authors:  Zhang, Li-fan;  Yu, Xiao-lin;  Ji, Mei;  Liu, Shu-ying;  Wu, Xiao-ling;  Wang, Yu-jiong;  Liu, Rui-tian
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Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-kappa B signaling pathway 期刊论文
BRAIN RESEARCH, 2018, 卷号: 1697, 页码: 21-33
Authors:  Liu, Shu-ying;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Xiang-meng;  Zhang, Yue;  Dong, Quan-xiu;  Ma, Shan;  Liu, Rui-tian
Adobe PDF(4079Kb)  |  Favorite  |  View/Download:47/0  |  Submit date:2018/10/11
Huntington's Disease  Polyglutamine  Intravenous Immunoglobulin  Huntingtin Protein  
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia 期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
Authors:  Ji, Mei;  Xie, Xi-xiu;  Liu, Dong-qun;  Yu, Xiao-lin;  Zhang, Yue;  Zhang, Ling-xiao;  Wang, Shao-wei;  Huang, Ya-ru;  Liu, Rui-tian
Adobe PDF(3636Kb)  |  Favorite  |  View/Download:68/0  |  Submit date:2018/07/17
Alzheimer's Disease  Frontotemporal Dementia  Hepatitis b Core Protein  Truncated Tau  Neurofibrillary Tangles  Virus-like Particles (Vlps)  Vaccine  
小胶质细胞对阿尔兹海默病发生发展的影响作用 期刊论文
过程工程学报, 2018, 卷号: 18, 期号: 05, 页码: 900-907
Authors:  刘小歌;  张伦;  于晓琳
Adobe PDF(970Kb)  |  Favorite  |  View/Download:36/0  |  Submit date:2019/06/17
小胶质细胞  阿尔兹海默病  Β淀粉样蛋白  突触  神经炎症  
Intravenous immunoglobulin improves glucose control and beta-cell function in human IAPP transgenic mice by attenuating islet inflammation and reducing IAPP oligomers 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 54, 页码: 145-152
Authors:  Zhang, Yue;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Shu-ying;  Liu, Xiang-meng;  Dong, Quan-xiu;  Chai, Jia-qian;  Liu, Rui-tian
Favorite  |  View/Download:51/0  |  Submit date:2018/06/11
Type 2 Diabetes Mellitus  Intravenous Immunoglobulin  Islet Amyloid Polypeptide  Islet Inflammation  Toxic Oligomer  
Therapeutic vaccine against IL-1 beta improved glucose control in a mouse model of type 2 diabetes 期刊论文
LIFE SCIENCES, 2018, 卷号: 192, 期号: 00, 页码: 68-74
Authors:  Zhang, Yue;  Yu, Xiao-lin;  Zha, Jun;  Mao, Li-zhen;  Chai, Jia-qian;  Liu, Rui-tian
Adobe PDF(1102Kb)  |  Favorite  |  View/Download:66/0  |  Submit date:2018/01/19
Type 2 Diabetes  Islet Inflammation  Il-1 Beta  Therapeutic Vaccine